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Gene Expression Data
Assay Details
Assay
Reference: J:227617 Garrett AM, et al., Analysis of Expression Pattern and Genetic Deletion of Netrin5 in the Developing Mouse. Front Mol Neurosci. 2016;9:3
Assay type: RNA in situ
MGI Accession ID: MGI:6279941
Gene symbol: Ntn5
Gene name: netrin 5
Probe: Ntn5 probe2
Probe preparation: DNA
Results
Specimen E11.5 not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: spinal component of peripheral nervous system Present Authors state expression was detectable at E11.5.
Specimen 1E: embryonic day 15.5 (more )
Note: Double labeled: red - Ntn5; blue - Chat (assay MGI:6279943).
Structure Level Pattern Image Note
TS23: spinal component of peripheral nervous system Strong Regionally restricted 1E Strong expression at the dorsal root entry zone (DREZ) of spinal cord. Expression adjacent to the motor exit point (MEP).
Specimen 1F: embryonic day 15.5 (more )
Note: Double labeled: red - Ntn5; blue - Egr2 (assay MGI:6279944).
Structure Level Pattern Image Note
TS23: spinal component of peripheral nervous system Present Regionally restricted 1F Expression at dorsal root entry zone (DREZ) of spinal cord.
Specimen 1G: embryonic day 15.5 (more )
Note: Double labeled: red - Ntn5; blue - Egr2 (assay MGI:6279944).
Structure Level Pattern Image Note
TS23: spinal component of peripheral nervous system Present Regionally restricted 1G Expression at motor exit point (MEP).
Specimen 1H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: spinal component of peripheral nervous system Strong Regionally restricted 1H Peak expression at dorsal root entry zone (DREZ) between E13.5 and E17.5.
Specimen 1I: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: spinal component of peripheral nervous system Strong Regionally restricted 1I Peak expression at dorsal root entry zone (DREZ) between E13.5 and E17.5.
Specimen 1J: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: spinal component of peripheral nervous system Weak Regionally restricted 1J Dimitished expression at dorsal root entry zone (DREZ)
Specimen 1K: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: spinal component of peripheral nervous system Strong Regionally restricted 1K Strongest expression at motor exit point (MEP) between E13.5 and E17.5.
Specimen 1L: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: spinal component of peripheral nervous system Strong Regionally restricted 1L Strongest expression at motor exit point (MEP) between E13.5 and E17.5.
Specimen 1M: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: spinal component of peripheral nervous system Trace Regionally restricted 1M Barely detectable expression at motor entry point (MEP).
Specimen 2G: embryonic day 13.5; Ntn5tm1.1Rwb/Ntn5tm1.1Rwb (more )
Note: Double labeled: red - Ntn5; blue - Egr2 (assay MGI:6279944).
Structure Level Pattern Image Note
TS21: spinal component of peripheral nervous system Absent 2G No expression in boundary cap cells (BCC) at dorsal root entry zone (DREZ) in mutant embryos.
Specimen 2J: embryonic day 13.5; Ntn5tm1.1Rwb/Ntn5tm1.1Rwb (more )
Note: Double labeled: red - Ntn5; blue - Egr2 (assay MGI:6279944).
Structure Level Pattern Image Note
TS21: spinal component of peripheral nervous system Absent 2J No expression in boundary cap cells (BCC) at motor entry point (MEP) in mutant embryos.
Specimen S2A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: head Present Regionally restricted S2A Authors report expression adjacent to the brain.
TS19: tail Present S2A
Specimen S2B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: olfactory system Present S2B Expression associated with the olfactory system.
Specimen S2C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: tail Present S2C
Specimen S2D: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: head Present Regionally restricted S2D Authors report expression adjacent to the brain.
TS25: olfactory system Present S2D Expression associated with the olfactory system.
TS25: vibrissa Present Regionally restricted S2D Expression at the base of whiskers in the chin.
TS25: tail Present S2D
Specimen S2E: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: vibrissa Present Regionally restricted S2E Expression at the base of whiskers in the chin.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory