About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:187541 Schievenbusch S, et al., Neighbor of punc e 11: expression pattern of the new hepatic stem/progenitor cell marker during murine liver development. Stem Cells Dev. 2012 Sep 20;21(14):2656-66
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6278253
Gene symbol: Igdcc4
Gene name: immunoglobulin superfamily, DCC subclass, member 4
Antibody: anti-Nope (AF1394)
Detection system: Cy3
Assay notes: Tissue sections were fixed in ice-cold acetone.
Results
Specimen 3A/D: embryonic day 14.5 (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - E-Cadherin (Cdh1; assay MGI:6278255); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS22: liver Present Regionally restricted 3A , 3D Expression restricted to bipotential hepatoblasts.
Specimen 3E/H: embryonic day 17.5 (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - E-Cadherin (Cdh1; assay MGI:6278255); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS25: liver Present Regionally restricted 3H , 3E Expression in differentiated committed progenitor cells.
Specimen 3I/L: postnatal week 1 (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - E-Cadherin (Cdh1; assay MGI:6278255); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS28: liver Present Regionally restricted 3I , 3L Expression in early Cdh1-positive hepatocytes.
Specimen 3M/P: postnatal adult (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - E-Cadherin (Cdh1; assay MGI:6278255); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS28: liver Present Regionally restricted 3P , 3M No expression in differentiated hepatocytes.
Specimen 4A/D: embryonic day 14.5 (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - CK19 (Krt19; assay MGI:6278257); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS22: liver Present Regionally restricted 4D , 4A Expression restricted to bipotential hepatoblasts.
Specimen 4E/H: embryonic day 17.5 (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - CK19 (Krt19; assay MGI:6278257); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS25: liver Present Regionally restricted 4H , 4E Expression not restricted to hepatocyte progenitor cells.
TS25: bile duct Present Regionally restricted 4E , 4H Expression clearly detectable in early bile ducts (committed cholangiocytic progenitor cells).
Specimen 4I/L: postnatal week 1 (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - CK19 (Krt19; assay MGI:6278257); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS28: bile duct Present Regionally restricted 4L , 4I Expression in early cholangiocytes.
Specimen 4M/P: postnatal adult (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - CK19 (Krt19; assay MGI:6278257); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS28: bile duct Present Regionally restricted 4M , 4P Expression in differentiated cholangiocytes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory