Reporter:	lacZ
	Direct Detection

Structure	Level	Pattern	Image	Note
TS20: oral region epithelium	Present	Regionally restricted	2A	Expressed in the salivary gland epithelia.
TS20: buccal pouch	Present	Regionally restricted	2A	Expressed in the epithelial component of the juxta-oral organ, which invaginates from oral epithelium into buccal submucosal connective tissue and separates from oral epithelium to form an epithelial cord.
TS20: cornea epithelium	Present		2A
TS20: epidermis	Present		2A
TS20: oral epithelium	Present		2A
TS20: eye epithelium	Present	Regionally restricted	2A	Expressed in conjunctival epithelium.

Structure	Level	Pattern	Image	Note
TS20: buccal pouch	Present	Regionally restricted	2B	Expressed in the epithelial component of the juxta-oral organ, which invaginates from oral epithelium into buccal submucosal connective tissue and separates from oral epithelium to form an epithelial cord.

Structure	Level	Pattern	Image	Note
TS20: buccal pouch	Present	Regionally restricted	2C	Expressed in the epithelial component of the juxta-oral organ, which invaginates from oral epithelium into buccal submucosal connective tissue and separates from oral epithelium to form an epithelial cord. The entire juxta-oral organ between the anterior and posterior ends is located within the buccal submucosal space.

Structure	Level	Pattern	Image	Note
TS20: oral region epithelium	Present	Regionally restricted	2D	Expressed in the epithelial component of the juxta-oral organ. The anterior end extends toward the angle of the mouth and then begins to bend ventrally to approach the budding of the parotid gland (LacZ stained too).

Structure	Level	Pattern	Image	Note
TS20: oral region epithelium	Present	Regionally restricted	2E	Expressed in the epithelial component of the juxta-oral organ. The posterior end extends into the submucosal tissue of the developing palatine shelf.

Structure	Level	Pattern	Image	Note
TS21: oral region epithelium	Present	Regionally restricted	2F	Expressed in the epithelial component of the juxta-oral organ, which located parallel to the parotid duct. Extension of the anterior portion has almost stopped.
TS21: salivary gland epithelium	Present		2F	Expressed in the parotid duct, which extends temporally to extend to the temple near the external ear and begins to spread branches for terminal acini.

Structure	Level	Pattern	Image	Note
TS21: oral region epithelium	Present	Regionally restricted	2G	Expressed in the epithelial component of the juxta-oral organ. The posterior end begins to bend posteriorly after it extends medially into the submucosal tissue of the palatine shelf.

Structure	Level	Pattern	Image	Note
TS23: oral region epithelium	Present	Regionally restricted	2H	Expressed in the epithelial component of the juxta-oral organ. Extension of the anterior portion has almost stopped.
TS23: parotid gland epithelium	Present		2H	The parotid gland epithelium continues to extend to the temple near the external ear and begins to spread branches for terminal acini.

Structure	Level	Pattern	Image	Note
TS23: oral region epithelium	Present	Regionally restricted	2I	Expressed in the epithelial component of the juxta-oral organ. Extension of the anterior portion has almost stopped, finally located in the submucosal space in the soft palate, anterior to the choanae.

Structure	Level	Pattern	Image	Note
TS25: oral region epithelium	Present	Regionally restricted	3A	Expressed in the epithelial component of the juxta-oral organ. No significant morphological changes are seen, compared with E15.5. The middle portion run anterior to the mandibular ramus and medial to the masseter, passed beneath the zygomatic arch and reaches the orbit.
TS25: parotid gland epithelium	Present		3A
TS25: eye gland	Present	Regionally restricted	3A	Expressed in the lacrimal gland.

Structure	Level	Pattern	Image	Note
TS25: oral region epithelium	Present	Regionally restricted	3B	Expressed in the epithelial component of the juxta-oral organ. The distribution of the anterior and middle portions from mandible to orbit was the same in heterozygous and homozygous animals. Staining was generally more intense in the homozygous animals.
TS25: eye gland	Present	Regionally restricted	3B	Expressed in the lacrimal gland.
TS25: parotid gland epithelium	Present		3B

Structure	Level	Pattern	Image	Note
TS25: oral region epithelium	Present	Regionally restricted	3C	Expressed in the epithelial component of the juxta-oral organ, which located on the anterior fascia of the temporal muscle and curved steeply inwards running posterio-medially to reach the soft palate. The junction of the anterior and middle portions was observed in the posterior wall of the orbit.
TS25: eye gland	Present	Regionally restricted	3C	Expressed in the lacrimal gland.
TS25: parotid gland epithelium	Present		3C

Structure	Level	Pattern	Image	Note
TS25: parotid gland epithelium	Present		3D	A small single bud sprouting from the middle of the parotid duct toward the junction of the anterior and middle portions of the juxta-oral organ.
TS25: oral region epithelium	Present	Regionally restricted	3D	Expressed in the epithelial component of the juxta-oral organ. The anterior portion was parallel to a pair of blood vessels. Also expressed in anterior buccal gland.

Structure	Level	Pattern	Image	Note
TS27: oral region epithelium	Present	Regionally restricted	3E	Expressed in the epithelial component of the juxta-oral organ. The middle portion run anterior to the mandibular ramus and medial to the masseter, passed beneath the zygomatic arch and reaches the orbit. The anterior portion near the anterior-middle junction is somewhat thickened.
TS27: lacrimal gland	Present		3E
TS27: parotid gland epithelium	Present		3E

Structure	Level	Pattern	Image	Note
TS27: oral region epithelium	Present	Regionally restricted	3F	Expressed in the juxta-oral organ.

Structure	Level	Pattern	Image	Note
TS27: oral region epithelium	Present	Regionally restricted	3G	Expressed in the juxta-oral organ.

Structure	Level	Pattern	Image	Note
TS27: oral region epithelium	Present	Regionally restricted	3G inset	Expressed in the juxta-oral organ, which extended further posteriorly in the soft palate and closer to the choanae.

Structure	Level	Pattern	Image	Note
TS27: lacrimal gland	Present		3H
TS27: parotid gland epithelium	Present		3H
TS27: oral region epithelium	Present	Regionally restricted	3H	Expressed in the epithelial component of the juxta-oral organ. The middle portion ran parallel to the anterior surface of the mandible and went beneath the parotid duct and then the zygomatic arch before reaching the orbit.

Structure	Level	Pattern	Image	Note
TS27: parotid gland epithelium	Present		3I
TS27: oral region epithelium	Present	Regionally restricted	3I	Expressed in the epithelial component of the juxta-oral organ. The posterior portion was located in the soft palate posterior to the palatine bone and lateral to the pterygoid bone. The growth of the posterior part on the right and left sides differs in this case.

Structure	Level	Pattern	Image	Note
TS28: oral region epithelium	Present	Regionally restricted	4A	Expressed in the juxta-oral organ. The anterior portion was located at the antero-inferior margin of the superficial masseter.

Structure	Level	Pattern	Image	Note
TS28: oral region epithelium	Present	Regionally restricted	4B	Expressed in the juxta-oral organ. The anterior portion was located at the antero-inferior margin of the superficial masseter. It was observed between the mandible and the fascia of the superficial masseter muscle and is parallel to the facial artery and vein.

Structure	Level	Pattern	Image	Note
TS28: oral region epithelium	Present	Regionally restricted	4C	Expressed in the juxta-oral organ. The anterior portion was located at the antero-inferior margin of the superficial masseter.

Structure	Level	Pattern	Image	Note
TS28: oral region epithelium	Present	Regionally restricted	4D	Expressed in the juxta-oral organ. The middle portion runs medial to the deep masseter muscle in its lower half and on the anterior fascia of the temporalis in its upper half.

Structure	Level	Pattern	Image	Note
TS28: oral region epithelium	Present	Regionally restricted	4E	Expressed in the juxta-oral organ. The junction between the middle and posterior portions is observed on the infero-posterior wall of the orbit, and turns steeply on the anterior fascia of the temporal muscle.

Structure	Level	Pattern	Image	Note
TS28: oral region epithelium	Present	Regionally restricted	4F	Expressed in the juxta-oral organ. The lower half of the middle portion is located closely parallel to the buccal nerve.

Structure	Level	Pattern	Image	Note
TS28: oral region epithelium	Present	Regionally restricted	4G	Expressed in the juxta-oral organ. The posterior portion descends on the anterior surface of the temporal muscle, then runs distal to the third molar and crosses medially over the alveolar arch of the maxilla. Finally, it reaches into the submucosal space of the soft palate.

Structure	Level	Pattern	Image	Note
TS28: oral region epithelium	Present	Regionally restricted	4H	Expressed in the juxta-oral organ. The posterior portion descends on the anterior surface of the temporal muscle, then runs distal to the third molar and crosses medially over the alveolar arch of the maxilla. Finally, it reaches into the submucosal space of the soft palate.

Structure	Level	Pattern	Image	Note
TS27: oral region epithelium	Present	Regionally restricted		Expressed in the juxta-oral organ. No sex difference in the shape, development and intensity of the staining.

Structure	Level	Pattern	Image	Note
TS27: oral region epithelium	Present	Regionally restricted		Expressed in the juxta-oral organ. No sex difference in the shape, development and intensity of the staining.

Structure	Level	Pattern	Image	Note
TS28: oral region epithelium	Present	Regionally restricted		Expressed in the juxta-oral organ. No sex difference in the shape, development and intensity of the staining.

Structure	Level	Pattern	Image	Note
TS28: oral region epithelium	Present	Regionally restricted		Expressed in the juxta-oral organ. No sex difference in the shape, development and intensity of the staining.