Gene Expression Data
Assay Details
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Assay
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Reference:
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J:154906
Wang W, et al., Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription. Development. 2009 Dec;136(24):4143-53
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6273215
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Gene symbol:
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Atf4
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Gene name:
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activating transcription factor 4
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Results
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Specimen
1D WT:
embryonic day 14.5
(more  )
Specimen
1D WT:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: humerus cartilage condensation |
Present |
Regionally restricted |
1D WT
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Expression in all growth plate chondrocytes. High levels of expression in perichondrium, proliferative and prehypertrophic chondrocytes.
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Specimen
1D -/-:
(close )
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Genetic Background:
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involves: 129
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Mutant Allele(s):
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Atf4tm1Tow/Atf4tm1Tow
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
S1A WT:
embryonic day 16.5
(more )
Specimen
S1A WT:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: humerus |
Present |
Regionally restricted |
S1A WT
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Expression in wild type chondrocytes.
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Specimen
S1A -/-:
(close )
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Genetic Background:
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involves: 129
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Mutant Allele(s):
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Atf4tm1Tow/Atf4tm1Tow
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Age:
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embryonic day 16.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: humerus |
Absent |
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S1A -/-
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No expression in mutant chondrocytes.
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Analysis Tools
