Bcl11a Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:237333 Dias C, et al., BCL11A Haploinsufficiency Causes an Intellectual Disability Syndrome and Dysregulates Transcription. Am J Hum Genet. 2016 Aug 04;99(2):253-74
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6272878
Gene symbol:	Bcl11a
Gene name:	BCL11 transcription factor A

Antibody:	Anti-Ctip1/BCL-11A antibody [18B12DE6] (ab19489)
Detection system:	Secondary antibody coupled to Alexa Fluor 594

Results

S1E ©

Specimen S1E: postnatal adult; Bcl11a^tm1Peli/Bcl11a⁺ (more

)

Structure	Level	Image
TS28: CA1 pyramidal cell layer	Strong	S1E
TS28: CA2 pyramidal cell layer	Strong	S1E
TS28: CA3 pyramidal cell layer	Strong	S1E
TS28: dentate gyrus granule cell layer	Strong	S1E
TS28: cortical layer II	Present	S1E
TS28: cortical layer III	Present	S1E
TS28: cortical layer IV	Present	S1E
TS28: cortical layer V	Present	S1E
TS28: cortical layer VI	Present	S1E
TS28: thalamus	Present	S1E
TS28: cortical layer I	Absent	S1E

S1F ©

Specimen S1F: postnatal adult; Bcl11a^tm3Peli/Bcl11a^tm1Peli (more

)

Structure	Level	Image
TS28: CA1 pyramidal cell layer	Strong	S1F
TS28: CA2 pyramidal cell layer	Strong	S1F
TS28: CA3 pyramidal cell layer	Strong	S1F
TS28: dentate gyrus granule cell layer	Strong	S1F
TS28: cortical layer II	Present	S1F
TS28: cortical layer III	Present	S1F
TS28: cortical layer IV	Present	S1F
TS28: cortical layer V	Present	S1F
TS28: cortical layer VI	Present	S1F
TS28: thalamus	Present	S1F
TS28: cortical layer I	Absent	S1F

S3A left ©

S3A merge ©

Specimen S3A: postnatal adult; Bcl11a^tm3Peli/Bcl11a^tm1Peli (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Present		S3A left , S3A merge

S3B left ©

S3B merge ©

Specimen S3B: postnatal adult; Bcl11a^tm1Peli/Bcl11a⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Present		S3B merge , S3B left

S3C left ©

S3C merge ©

Specimen S3C: postnatal adult; Bcl11a^tm3Peli/Bcl11a^tm1Peli (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Present		S3C merge , S3C left

S3D left ©

S3D merge ©

Specimen S3D: postnatal adult; Bcl11a^tm1Peli/Bcl11a⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Present		S3D merge , S3D left

S8E ©

Specimen S8E: postnatal adult; Bcl11a^tm1Peli/Bcl11a⁺ (more

)

Structure	Level	Image
TS28: cortical layer II	Present	S8E
TS28: cortical layer III	Present	S8E
TS28: cortical layer IV	Present	S8E
TS28: cortical layer V	Present	S8E
TS28: cortical layer VI	Present	S8E
TS28: cortical layer I	Absent	S8E

S8F ©

Specimen S8F: postnatal adult; Bcl11a^tm3Peli/Bcl11a^tm1Peli (more

)

Structure	Level	Image	Note
TS28: cortical layer II	Present	S8F	More stained nuclei in deep layers in comparison to upper layers.
TS28: cortical layer III	Present	S8F	More stained nuclei in deep layers in comparison to upper layers.
TS28: cortical layer IV	Present	S8F	More stained nuclei in deep layers in comparison to upper layers.
TS28: cortical layer V	Present	S8F	More stained nuclei in deep layers in comparison to upper layers.
TS28: cortical layer VI	Present	S8F	More stained nuclei in deep layers in comparison to upper layers.
TS28: cortical layer I	Absent	S8F

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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