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Gene Expression Data
Assay Details
Assay
Reference: J:264805 Brutsch SH, et al., Expression of inactive glutathione peroxidase 4 leads to embryonic lethality, and inactivation of the Alox15 gene does not rescue such knock-in mice. Antioxid Redox Signal. 2015 Feb 1;22(4):281-93
Assay type: RT-PCR
MGI Accession ID: MGI:6258630
Gene symbol: Gpx4
Gene name: glutathione peroxidase 4
Probe: m+c-GPx4 primers
Probe preparation: labelled with SYBR green
Assay notes: Quantitative real-time PCR. Relative expression is shown normalized to beta-actin expression. Primers amplified the cytosolic isoform.
Results Image: 3A c-Gpx4
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
U46A-/- P TS28: liver Present Not Specified; total RNA Not Specified Not Specified
-/+ P TS28: liver Present (a) Not Specified; total RNA involves: 129S6/SvEvTac * C57BL/6NTac Gpx4tm1.1Adbo/Gpx4+Not Specified
U46A-/- P TS28: brain Present Not Specified; total RNA Not Specified Not Specified
-/+ P TS28: brain Present (a) Not Specified; total RNA involves: 129S6/SvEvTac * C57BL/6NTac Gpx4tm1.1Adbo/Gpx4+Not Specified
U46A-/- P TS28: spleen Present Not Specified; total RNA Not Specified Not Specified
-/+ P TS28: spleen Present (a) Not Specified; total RNA involves: 129S6/SvEvTac * C57BL/6NTac Gpx4tm1.1Adbo/Gpx4+Not Specified
U46A-/- P TS28: metanephros Present Not Specified; total RNA Not Specified Not Specified
-/+ P TS28: metanephros Present (a) Not Specified; total RNA involves: 129S6/SvEvTac * C57BL/6NTac Gpx4tm1.1Adbo/Gpx4+Not Specified
U46A-/- P TS28: lung Present Not Specified; total RNA Not Specified Not Specified
-/+ P TS28: lung Present (a) Not Specified; total RNA involves: 129S6/SvEvTac * C57BL/6NTac Gpx4tm1.1Adbo/Gpx4+Not Specified
U46A-/- P TS28: heart Present Not Specified; total RNA Not Specified Not Specified
-/+ P TS28: heart Present (a) Not Specified; total RNA involves: 129S6/SvEvTac * C57BL/6NTac Gpx4tm1.1Adbo/Gpx4+Not Specified
Notes:
(a) Expression in the heterozygote is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory