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Gene Expression Data
Assay Details
Assay
Reference: J:240035 Roux M, et al., Hoxa1 and Hoxb1 are required for pharyngeal arch artery development. Mech Dev. 2017 Feb;143:1-8
Assay type: RNA in situ
MGI Accession ID: MGI:6257900
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Probe: Sox10 probe18
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 6G: embryonic day 9.5; Hoxa1tm1Ipc/Hoxa1+ (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted 6G Authors report normal migration of neural crest cells to 3rd and 4th pharyngeal arch arteries.
Specimen 6H: embryonic day 9.5; Hoxb1tm5Mrc/Hoxb1+ (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted 6H Authors report normal migration of neural crest cells to 3rd and 4th pharyngeal arch arteries.
Specimen 6I: embryonic day 9.5; Hoxa1tm1Ipc/Hoxa1+, Hoxb1tm5Mrc/Hoxb1+ (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted 6I Authors report abnormal post-otic streams of migrating neural crest cells.
Specimen 6J: embryonic day 9.5; Hoxb1tm5Mrc/Hoxb1tm5Mrc (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted 6J Authors report normal migration of neural crest cells to 3rd and 4th pharyngeal arch arteries.
Specimen 6K: embryonic day 9.5; Hoxa1tm1Ipc/Hoxa1+, Hoxb1tm5Mrc/Hoxb1tm5Mrc (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted 6K Authors report abnormal post-otic streams of migrating neural crest cells.
Specimen 6L: embryonic day 9.5; Hoxa1tm1Ipc/Hoxa1tm1Ipc, Hoxb1tm5Mrc/Hoxb1tm5Mrc (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted 6L Authors report neural crest migration defect was more severe in absence of both Hoxa1 and Hoxb1.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory