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Gene Expression Data
Assay Details
Assay
Reference: J:194075 Guenatri M, et al., Plasticity in Dnmt3L-dependent and -independent modes of de novo methylation in the developing mouse embryo. Development. 2013 Feb 1;140(3):562-72
Assay type: Western blot
MGI Accession ID: MGI:6201102
Gene symbol: Dnmt3a
Gene name: DNA methyltransferase 3A
Antibody: Anti-Dnmt3a (ab13888)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Size Not Specified Genetic BackgroundMutant Allele(s)Sex
ES-cells Cultured cells: no data stored
E6.5-Dnmt3lwt E6.5 TS9: embryo Present Present Not Specified Not Specified
E6.5-Dnmt3lz- E6.5 TS9: embryo Present (b) Present (c) involves: 129S6/SvEvTac Dnmt3ltm1Bes/Dnmt3ltm1BesNot Specified
Notes:
(a) Dnmt3A2 - the short, most active isoform.
(b) The Dnmt3A2 isoform is upregulated in mutant compared to wild type.
(c) The protein is upregulated in mutant compared to wild type.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory