Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Spatc1lem1Choc
Name:	spermatogenesis and centriole associated 1 like; endonuclease-mediated mutation 1, Chunghee Cho
MGI ID:	MGI:6200789
Gene:	Spatc1l  Location: Chr10:76398106-76406035 bp, + strand  Genetic Position: Chr10, 39.2 cM
Alliance:	Spatc1lem1Choc page

Strain of Origin:

C57BL/6N

Allele Type:    Endonuclease-mediated (Null/knockout) Mutation:    Intragenic deletion   Mutation details: CRISPR/Cas9 mediated recombination created a 178 bp deletion in exon 1 spanning the ATG start site. PCR and immunoblot analysis confirmed the absence of RNA and protein expression in testes from homozygous mice. (J:265193)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Spatc1l Mutation:	16 strains or lines available

Original:	J:265193 Kim J, et al., SPATC1L maintains the integrity of the sperm head-tail junction. EMBO Rep. 2018 Sep;19(9)
All:	1 reference(s)