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Gene Expression Data
Assay Details
Assay
Reference: J:248203 Diggle CP, et al., A tubulin alpha 8 mouse knockout model indicates a likely role in spermatogenesis but not in brain development. PLoS One. 2017;12(4):e0174264
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6197538
Gene symbol: Tuba8
Gene name: tubulin, alpha 8
Results
Specimen +/+ cortex not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present

Specimen -/- cortex not shown: postnatal adult; Tuba8tm1.2Ctpd/Tuba8tm1.2Ctpd (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present No difference in expression between genotypes.

Specimen 2A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong Regionally restricted 2A Expression in Purkinje cell dendrites.

Specimen 2B: postnatal adult; Tuba8tm1.2Ctpd/Tuba8tm1.2Ctpd (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Weak Regionally restricted 2B Expression in Purkinje cell dendrites. Authors report difference in labeling intensity.

Specimen 2C/D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: testis Present Regionally restricted 2D , 2C Authors report localization of expression in testis was very clearly cell-type restricted.

Specimen 2E: postnatal adult; Tuba8tm1.2Ctpd/Tuba8tm1.2Ctpd (more )
Structure Level Pattern Image Note
TS28: testis Absent 2E

Specimen S5A/C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present Punctate S5C , S5A
TS28: heart endothelium Absent S5C , S5A

Specimen S5B/D: postnatal adult; Tuba8tm1.2Ctpd/Tuba8tm1.2Ctpd (more )
Structure Level Pattern Image Note
TS28: heart Absent S5D , S5B


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory