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Gene Expression Data
Assay Details
Assay
Reference: J:135997 Nie X, et al., Disruption of Smad4 in neural crest cells leads to mid-gestation death with pharyngeal arch, craniofacial and cardiac defects. Dev Biol. 2008 Apr 15;316(2):417-30
Assay type: RNA in situ
MGI Accession ID: MGI:6193727
Gene symbol: Tbx1
Gene name: T-box 1
Probe: Tbx1 probe8
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7Q: embryonic day 10.0; Smad4tm2.1Cxd/Smad4+ (more )
Structure Level Pattern Image Note
TS16: 1st branchial arch Present 7Q
TS16: 2nd branchial arch Present 7Q
Specimen 7R: embryonic day 10.0; Smad4tm2.1Cxd/Smad4tm2.1Cxd, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS16: 1st branchial arch Weak 7R Noticeably reduced expression in first and second pharyngeal arches.
TS16: 2nd branchial arch Weak 7R Noticeably reduced expression in first and second pharyngeal arches.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory