Gene Expression Data
Assay Details
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Assay
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Reference:
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J:132568
Glotzer DJ, et al., Impaired skin and hair follicle development in Runx2 deficient mice. Dev Biol. 2008 Mar 15;315(2):459-73
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:6191616
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Gene symbol:
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Runx2
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Gene name:
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runt related transcription factor 2
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
1A:
embryonic day 17.5; Runx2tm1Mjo/Runx2 +
(more  )
Note: Stage 2 hair follicles
Specimen
1A:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Runx2tm1Mjo/Runx2+
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Stage 2 hair follicles
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: hair follicle |
Present |
Punctate |
1A
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Expression as punctate dots or ovals.
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Specimen
1B:
embryonic day 18.5; Runx2tm1Mjo/Runx2 +
(more )
Note: Stage 4 and 5 hair follicles
Specimen
1B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Runx2tm1Mjo/Runx2+
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Stage 4 and 5 hair follicles
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: hair follicle |
Present |
Regionally restricted |
1B
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Authors report differences in the amount of expression from follicle to follicle.
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Specimen
1C:
embryonic day 18.5; Runx2tm1Mjo/Runx2 +
(more )
Note: Stage 5 hair follicles
Specimen
1C:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Runx2tm1Mjo/Runx2+
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Stage 5 hair follicles
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Specimen
1D:
embryonic day 19.0; Runx2tm1Mjo/Runx2 +
(more )
Note: Stage 5 hair follicle
Specimen
1D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Runx2tm1Mjo/Runx2+
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Age:
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embryonic day 19.0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Stage 5 hair follicle
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: hair follicle |
Present |
Regionally restricted |
1D
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Expression in epithelium of hair follicle.
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| TS26: hair bulb |
Present |
Regionally restricted |
1D
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Authors state epithelial expression is typically asymmetrical, predominantly on the superficial side of the follicle bulb.
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Analysis Tools
