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Gene Expression Data
Assay Details
Assay
Reference: J:215602 Lai YJ, et al., TRIP6 regulates neural stem cell maintenance in the postnatal mammalian subventricular zone. Dev Dyn. 2014 Sep;243(9):1130-42
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6162670
Gene symbol: Trip6
Gene name: thyroid hormone receptor interactor 6
Antibody: anti-ZRP-1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2A/B/C: embryonic day 16.5 (more )
Note: Double labeled: green - Trip6; red - Sox2 (assay MGI:6162669).
Structure Level Pattern Image Note
TS24: cerebral cortex Present Graded 2A merge , 2A TRIP6 , 2B merge , 2B TRIP6 Expressed in a ventricle-to-mantle gradient. The percentage of positive cells that also express Sox2 was 90.2+/-2.7%.
TS24: corpus striatum Present Graded 2C TRIP6 , 2A TRIP6 , 2C merge , 2A merge Expressed in a ventricle-to-mantle gradient. The percentage of positive cells that also express Sox2 was 90.2+/-2.7%.
Specimen 2D: embryonic day 16.5 (more )
Note: Double labeled: green - Trip6; red - Mki67 (assay MGI:6162671).
Structure Level Pattern Image Note
TS24: cerebral cortex ventricular layer Present 2D TRIP6 , 2D merge 34.1+/-2.1% of positive cells were labeled with Mki67.
Specimen 3A: postnatal adult (more )
Note: Double labeled: green - Trip6; red - Sox2 (assay MGI:6162669).
Structure Level Pattern Image Note
TS28: cerebral cortex subventricular zone Present 3A TRIP6 , 3A merge
Specimen 3B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus subgranular zone Absent 3B
Specimen 3C/D: postnatal adult (more )
Note: Double labeled: green - Trip6; red - Sox2 (assay MGI:6162669).
Structure Level Pattern Image Note
TS28: cerebral cortex subventricular zone Present 3D merge , 3D TRIP6 , 3C Most expressing cells were also Sox2-positive (62.7 +/-1.6%).
Specimen 3D': postnatal adult (more )
Note: Double labeled: green - Trip6; red - Sox2 (assay MGI:6162669).
Structure Level Pattern Image Note
TS28: cerebral cortex ventricular zone Present 3D' TRIP6 , 3D' merge Most expressing cells were also Sox2-positive (62.7 +/-1.6%).
Specimen 3E/F: postnatal adult (more )
Note: Double labeled: green - Trip6; red - Mki67 (assay MGI:6162671).
Structure Level Pattern Image Note
TS28: cerebral cortex subventricular zone Present 3F merge , 3F TRIP6 , 3E Only 8.0+/-0.3% of positive cells were labeled with Mki67.
Specimen 3G/H: postnatal adult (more )
Note: Double labeled: green - Trip6; red - S100b (assay MGI:6162672).
Structure Level Pattern Image Note
TS28: cerebral cortex subventricular zone Present 3H TRIP6 , 3G , 3H merge 44.4+/-1.5% of positive cells were labeled with S100b.
Specimen 4A: postnatal adult (more )
Note: Double labeled: green - Trip6; red - Dcx (assay MGI:6162673).
Structure Level Pattern Image Note
TS28: cerebral cortex subventricular zone Present 4A TRIP6 , 4A merge Only 6.7+/-1.8% of expressing cells were Dcx+.
Specimen 4B: postnatal adult (more )
Note: Double labeled: green - Trip6; red - Map2 (assay MGI:6162674).
Structure Level Pattern Image Note
TS28: cerebral cortex subventricular zone Present Regionally restricted 4B merge , 4B TRIP6 Not expressed in Map2+ neurons.
Specimen 4C: postnatal adult (more )
Note: Double labeled: green - Trip6; red - Gfap (assay MGI:6162675).
Structure Level Pattern Image Note
TS28: corpus callosum Present 4C merge , 4C TRIP6 Not expressed in Gfap+ astrocytes.
Specimen 4D: postnatal adult (more )
Note: Double labeled: green - Trip6; red - Aif1 (assay MGI:6162676).
Structure Level Pattern Image Note
TS28: cerebral cortex subventricular zone Present 4D merge , 4D TRIP6 Not expressed in Aif1+ microglia.
Specimen not shown: postnatal adult (more )
Note: Also stained for Gfap (assay MGI:6162675).
Structure Level Pattern Image Note
TS28: corpus striatum Present Not expressed in Gfap+ astrocytes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory