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Gene Expression Data
Assay Details
Assay
Reference: J:121343 Lahteenmaki M, et al., Increased apoptosis of parasympathetic but not enteric neurons in mice lacking GFRalpha2. Dev Biol. 2007 May 1;305(1):325-32
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6161683
Gene symbol: Uchl1
Gene name: ubiquitin carboxy-terminal hydrolase L1
Antibody: anti-PGP9.5
Detection system: Cy2
Assay notes: Two antibodies recognizing this gene were described. Antibody anti-PGP9.5 MGI:6161674 may have been used in this assay.
Results
Specimen 1a/c: embryonic day 17.5 (more )
Note: Double labeled: green - PGP9.5 (Uchl1); red - Ins1 (assay MGI:6161693) and Ins2 (assay MGI:6161694).
Structure Level Pattern Image Note
TS25: pancreas Strong Regionally restricted 1a , 1c Strong expression in intrapancreatic ganglia.
TS25: parasympathetic ganglion Strong Regionally restricted 1a , 1c Strong expression in intrapancreatic ganglia.
TS25: islets of Langerhans Trace 1c , 1a Authors report faint expression in islet cells.
Specimen 5a: embryonic day 17.5 (more )
Note: Double labeled: green - PGP9.5 (Uchl1); red - activated caspase-3 (Casp3; assay MGI:6161697).
Structure Level Pattern Image Note
TS25: myenteric nerve plexus Present 5a
Specimen 5b: embryonic day 17.5 (more )
Note: Double labeled: green - PGP9.5 (Uchl1); red - activated caspase-3 (Casp3; assay MGI:6161697).
Structure Level Pattern Image Note
TS25: paravertebral ganglion Present 5b
Specimen 5e/f: embryonic day 17.5 (more )
Note: Double labeled: green - PGP9.5 (Uchl1); red - activated caspase-3 (Casp3; assay MGI:6161697).
Structure Level Pattern Image Note
TS25: pancreas Present Regionally restricted 5e , 5f Expression in intrapancreatic ganglia.
TS25: parasympathetic ganglion Present Regionally restricted 5e , 5f Expression in intrapancreatic ganglia.
Specimen 5i/j: embryonic day 17.5; Gfra2tm1Msa/Gfra2tm1Msa (more )
Note: Double labeled: green - PGP9.5 (Uchl1); red - activated caspase-3 (Casp3; assay MGI:6161697).
Structure Level Pattern Image Note
TS25: pancreas Present Regionally restricted 5i , 5j Expression in intrapancreatic ganglia.
TS25: parasympathetic ganglion Present Regionally restricted 5i , 5j Expression in intrapancreatic ganglia.
Specimen 5l/m: postnatal day 0; Gfra2tm1Msa/Gfra2tm1Msa (more )
Note: Double labeled: green - PGP9.5 (Uchl1); red - activated caspase-3 (Casp3; assay MGI:6161697).
Structure Level Pattern Image Note
TS27: submandibular ganglion Present 5l , 5m
Specimen Supplementary Figure b: embryonic day 15.5 (more )
Note: Double labeled: green - PGP9.5 (Uchl1); red - activated caspase-3 (Casp3; assay MGI:6161697).
Structure Level Pattern Image Note
TS23: dorsal root ganglion Present Supplementary_b PGP9.5 , Supplementary_b merge
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory