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Gene Expression Data
Assay Details
Assay
Reference: J:121338 Driskell RR, et al., Wnt3a regulates Lef-1 expression during airway submucosal gland morphogenesis. Dev Biol. 2007 May 1;305(1):90-102
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6161237
Gene symbol: Lef1
Gene name: lymphoid enhancer binding factor 1
Antibody: anti-Lef-1
Detection system: fluorescein
Results
Specimen 1A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: nasal epithelium Present Regionally restricted 1A Nuclear expression in nasal epithelial gland buds.

Specimen 1B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: nasal epithelium Present Regionally restricted 1B Nuclear expression in nasal epithelial gland buds.

Specimen 1D: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: epidermis basal layer Present 1D Expression in basal layer of epidermis, hair placode and dermal condensate.
TS27: hair epidermal placode Present 1D Expression in basal layer of epidermis, hair placode and dermal condensate.
TS27: hair follicle dermal papilla Present 1D Expression in basal layer of epidermis, hair placode and dermal condensate.

Specimen 1E: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: trachea epithelium Present Regionally restricted 1E Nuclear expression in tracheal epithelial gland buds.

Specimen 1F: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: trachea epithelium Present Regionally restricted 1F Nuclear expression in tracheal epithelial gland buds.

Specimen 1H: postnatal day 1; Lef1tm1Rug/Lef1tm1Rug (more )
Structure Level Pattern Image Note
TS27: trachea epithelium Present Regionally restricted 1H Nuclear expression in tracheal epithelial gland buds.

Specimen 1I: postnatal day 1; AmelxRgsc888/Y (more )
Note: Triple labeled: green - Lef1; red - Krt14 (assay MGI:6161238); blue - DAPI.
Structure Level Pattern Image Note
TS27: epidermis basal layer Absent 1I merge , 1I Lef-1 No expression in hair follicle buds or basal epidermal layer.
TS27: hair follicle Absent 1I merge , 1I Lef-1 No expression in hair follicle buds or basal epidermal layer.

Specimen 3A: embryonic day 15.5; AmelxRgsc888/Y (more )
Structure Level Pattern Image Note
TS23: nasal epithelium Present Regionally restricted 3A Expression in basal cells of surface airway nasal epithelium.

Specimen 3B: embryonic day 15.5; Wnt3atm1Amc/Wnt3atm1Amc (more )
Structure Level Pattern Image Note
TS23: nasal epithelium Absent 3B No expression in nasal submucosal gland placodes.

Specimen 3C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: vibrissa follicle Present 3C Expression in developing vibrissa.

Specimen 3D: embryonic day 15.5; Wnt3atm1Amc/Wnt3atm1Amc (more )
Structure Level Pattern Image Note
TS23: vibrissa follicle Present 3D Expression in developing vibrissa.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory