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Tg(IgkV3-2*01)L16Fosm
Transgene Detail
Summary
Symbol: Tg(IgkV3-2*01)L16Fosm
Name: transgene insertion L16, Mary Foster
MGI ID: MGI:6156582
Synonyms: IGKV3 LC Tg, mLCV3-Tg
Transgene: Tg(IgkV3-2*01)L16Fosm  Location: unknown  
Alliance: Tg(IgkV3-2*01)L16Fosm page
Transgene
origin
Strain of Origin:  C57BL/6NHsd
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(IgkV3-2*01)L16Fosm expresses 1 gene
 
Mutation detailsThe transgene comprises the rearranged IGKV3-2*01 (formerly Vk21C)/Jk2 immunoglobulin kappa light chain from a hybridoma cell line. It encodes the light chain of antibodies generated in C57BL/6 mice against the antigenic NC1 domain from collagen type IV, alpha 3 (anti-alpha3(IV)NC1). (J:140740, J:261505)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:261505 Clark AG, et al., A murine Ig light chain transgene reveals IGKV3 gene contributions to anti-collagen types IV and II specificities. Mol Immunol. 2017 Nov;91:49-56
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory