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Gene Expression Data
Assay Details
Assay
Reference: J:251823 Takagishi M, et al., Daple Coordinates Planar Polarized Microtubule Dynamics in Ependymal Cells and Contributes to Hydrocephalus. Cell Rep. 2017 Jul 25;20(4):960-972
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6155673
Gene symbol: Dvl2
Gene name: dishevelled segment polarity protein 2
Antibody: anti-Dvl2 (#3216)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4E +/+: postnatal day 21 (more )
Note: Triple labeled: green - Dvl2; red - Ctnnb1 (assay MGI:6155669); blue - gamma tubulin.
Structure Level Pattern Image Note
TS28: lateral ventricle ependyma Present Spotted 4E Dvl2 +/+ (low mag) , 4E merge +/+ , 4E Dvl2 +/+ (high mag) Authors report spot localization of expression in wall of left ventricle. Expression localized to basal body clusters in ependymal cells.
Specimen 4E -/-: postnatal day 21; Ccdc88ctm1(KOMP)Mbp/Ccdc88ctm1(KOMP)Mbp (more )
Note: Triple labeled: green - Dvl2; red - Ctnnb1 (assay MGI:6155669); blue - gamma tubulin.
Structure Level Pattern Image Note
TS28: lateral ventricle ependyma Present Spotted 4E merge -/- , 4E Dvl2 -/- (high mag) , 4E Dvl2 -/- (low mag) Authors report that localization of expression was significantly decreased in mutant ependymal cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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