Gene Expression Data
Assay Details
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Assay
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Reference:
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J:49264
Beckers J, et al., Genetic analysis of a conserved sequence in the HoxD complex: regulatory redundancy or limitations of the transgenic approach?. Dev Dyn. 1998 Sep;213(1):1-11
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6154848
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Gene symbol:
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Hoxd12
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Gene name:
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homeobox D12
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Probe:
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Hox-4.7 probe2
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
not shown:
embryonic day 11.0
(more  )
Specimen
not shown:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: limb |
Present |
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Specimen
not shown:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Hoxdtm4Ddu/Hoxdtm4Ddu
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: limb |
Weak |
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Staining intensity was reduced in mutant limb, but there was no qualitative change in the distribution of the transcript domain.
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Specimen
4C:
embryonic day 11.5
(more )
Specimen
4C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4D:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Hoxdtm4.1Ddu/Hoxdtm4.1Ddu
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: forelimb bud |
Present |
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4D
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No changes in expression pattern were noted in the mutant.
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| TS19: hindlimb bud |
Present |
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4D
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No changes in expression pattern were noted in the mutant.
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| TS19: central nervous system |
Present |
Regionally restricted |
4D
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No changes in the anterior expression limit were noted in the mutant.
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| TS19: sclerotome |
Present |
Regionally restricted |
4D
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No changes in the anterior expression limit were noted in the mutant.
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Analysis Tools