About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:92327 Adamska M, et al., En1 and Wnt7a interact with Dkk1 during limb development in the mouse. Dev Biol. 2004 Aug 1;272(1):134-44
Assay type: RNA in situ
MGI Accession ID: MGI:6147813
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3B wildtype: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 3B wildtype Expression in zone of polarizing activity (ZPA) in posterior limb mesenchyme.
Specimen 3C wildtype: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate mesenchyme Present Regionally restricted 3C wildtype Expression in zone of polarizing activity (ZPA) in posterior limb mesenchyme.
Specimen 4A Shh: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present 4A Shh
Specimen 4B Shh: embryonic day 10.5; Wnt7atm1Amc/Wnt7atm1Amc (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Weak 4B Shh Authors report decreased expression at E10.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory