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Gene Expression Data
Assay Details
Assay
Reference: J:250078 Fujiwara K, et al., Deletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouse. Transl Psychiatry. 2016 Mar 29;6:e766
Assay type: RNA in situ
MGI Accession ID: MGI:6119707
Gene symbol: Kdm4b
Gene name: lysine (K)-specific demethylase 4B
Probe: Probe 1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Specimens were freshly frozen and fixed with 4% paraformaldehyde just prior to hybridization.
Results
Specimen 1a: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: brain Strong 1a
TS25: retina Strong 1a
TS25: organ system Weak 1a
Specimen 1b E15: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: basal ganglia Strong 1b E15
TS23: cerebellum Strong 1b E15
TS23: cerebral cortex Strong 1b E15
TS23: hippocampus Strong 1b E15
TS23: main olfactory bulb Strong 1b E15
TS23: brain Present Diffuse 1b E15
Specimen 1b E17: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: basal ganglia Strong 1b E17
TS25: cerebellum Strong 1b E17
TS25: cerebral cortex Strong 1b E17
TS25: hippocampus Strong 1b E17
TS25: main olfactory bulb Strong 1b E17
TS25: brain Present Diffuse 1b E17
Specimen 1b P1: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: basal ganglia Strong 1b P1
TS27: cerebellum Strong 1b P1
TS27: cerebral cortex Strong 1b P1
TS27: hippocampus Strong 1b P1
TS27: main olfactory bulb Strong 1b P1
TS27: brain Present Diffuse 1b P1
Specimen 1b P3: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: basal ganglia Strong 1b P3
TS27: cerebellum Strong 1b P3
TS27: cerebral cortex Strong 1b P3
TS27: hippocampus Strong 1b P3
TS27: main olfactory bulb Strong 1b P3
TS27: brain Present Diffuse 1b P3
Specimen 1b P5: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: basal ganglia Strong 1b P5
TS28: cerebellum Strong 1b P5
TS28: cerebral cortex Strong 1b P5
TS28: hippocampus Strong 1b P5
TS28: main olfactory bulb Strong 1b P5
TS28: brain Present Diffuse 1b P5
Specimen 1b P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: basal ganglia Strong 1b P7
TS28: cerebellum Strong 1b P7
TS28: cerebral cortex Strong 1b P7
TS28: hippocampus Strong 1b P7
TS28: main olfactory bulb Strong 1b P7
TS28: brain Present Diffuse 1b P7
Specimen 1b P14: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: basal ganglia Strong 1b P14
TS28: cerebellum Strong 1b P14
TS28: cerebral cortex Strong 1b P14
TS28: hippocampus Strong 1b P14
TS28: main olfactory bulb Strong 1b P14
TS28: brain Present Diffuse 1b P14
Specimen 1b 8 weeks: postnatal week 8 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present 1b 8 weeks
TS28: dentate gyrus Present 1b 8 weeks
TS28: hippocampus Present 1b 8 weeks
TS28: hippocampus CA1 Present 1b 8 weeks
TS28: hippocampus CA3 Present 1b 8 weeks
Specimen 1c left: postnatal adult (more )
Note: Double labeled: blue - Kdm4b; brown - Rbfox3 (assay MGI:6119709).
Structure Level Pattern Image Note
TS28: hippocampus Present 1c left
Specimen 1c right: postnatal adult (more )
Note: Double labeled: blue - Kdm4b; brown - Gfap (assay MGI:6119713).
Structure Level Pattern Image Note
TS28: hippocampus Present 1c right
Specimen 2b WT: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: brain Present 2b WT
Specimen 2b KO: postnatal day 0; Kdm4btm1.1Okad/Kdm4btm1.1Okad, Mapttm2(cre)Aha/Mapt+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: brain Absent 2b KO
Specimen S1a: postnatal adult (more )
Note: Double labeled: blue - Kdm4b; brown - Gad1 (assay MGI:6119728).
Structure Level Pattern Image Note
TS28: hippocampus Present S1a
Specimen S1b: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: ganglionic eminence Present S1b right , S1b
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory