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Gene Expression Data
Assay Details
Assay
Reference: J:235365 Yzaguirre AD, et al., Insights into blood cell formation from hemogenic endothelium in lesser-known anatomic sites. Dev Dyn. 2016 Oct;245(10):1011-28
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6117874
Gene symbol: Kit
Gene name: KIT proto-oncogene receptor tyrosine kinase
Antibody: anti-CD117 (2B8)
Detection system: Secondary antibody
Results
Specimen 1A: embryonic day 8.0 (more )
Note: Confocal Z-projection. Late headfold stage embryo. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS12: yolk sac Present 1Aiii
Specimen 1B: embryonic day 8.0 (more )
Note: Confocal Z-projection. Late headfold stage embryo. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS12: yolk sac Present 1Biii
Specimen 1C: embryonic day 8.0 (more )
Note: Single optical projection. Late headfold stage embryo. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS12: yolk sac Present 1Ciii
Specimen 3B: embryonic day 9.5 (more )
Note: Confocal Z-projection. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present Regionally restricted 3Biii Expression is in the proximal region of the vascular plexus in close proximity of the vitelline artery.
Specimen 3C: embryonic day 9.5 (more )
Note: Single optical projection. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present Regionally restricted 3Ciii Expression is in the proximal region of the vascular plexus in close proximity of the vitelline artery.
Specimen 3D: embryonic day 9.5 (more )
Note: Confocal Z-projection. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present Regionally restricted 3Diii Expression is in the proximal region of the vascular plexus in close proximity of the vitelline vein.
Specimen 3E: embryonic day 9.5 (more )
Note: Confocal Z-projection. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present Regionally restricted 3Eiii Expression is in the proximal region of the vascular plexus in close proximity of the vitelline vein.
Specimen 3G: embryonic day 10.5 (more )
Note: Confocal Z-projection. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Present Regionally restricted 3Giii
Specimen 3H: embryonic day 10.5 (more )
Note: Confocal Z-projection. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Present Regionally restricted 3Hiii
Specimen 3I: embryonic day 10.5 (more )
Note: Confocal Z-projection. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Present Regionally restricted 3Iiii , 3Jiii
Specimen 6A: embryonic day 8.0 (more )
Note: Confocal Z-projection. Late headfold stage embryo. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS12: blood vessel Present Regionally restricted 6Aiii Expression is in the vascular intersection among the placenta, yolk sac, and embryo.
TS12: yolk sac Present Regionally restricted 6Aiii Expression is in the vascular intersection among the placenta, yolk sac, and embryo.
TS28: placenta Present Regionally restricted 6Aiii Expression is in the vascular intersection among the placenta, yolk sac, and embryo.
TS12: primordial germ cell of yolk sac Present 6Aiii
Specimen 7A: embryonic day 9.5 (more )
Note: Confocal Z-projection. 25 somite pair embryo. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS15: blood vessel Present 7Ai , 7Aiii
Specimen 7B: embryonic day 9.5 (more )
Note: Confocal Z-projection. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS15: dorsal aorta Present 7Biii , 7Bi , 7Bi right panel
TS15: vitelline artery Present 7Biii , 7Bi , 7Bi right panel
TS15: primordial germ cell Present 7Bi , 7Bi right panel , 7Biii
Specimen 7C: embryonic day 9.5 (more )
Note: Single optical projection. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS15: dorsal aorta Present 7C
TS15: vitelline artery Present 7C
Specimen 7D: embryonic day 9.5 (more )
Note: Single optical projection. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS15: vitelline artery Present 7D
Specimen 8A: embryonic day 10.5 (more )
Note: Confocal Z-projection. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS17: umbilical artery embryonic part Present Regionally restricted 8Aiii Expression is in hematopoietic clusters.
Specimen 8B: embryonic day 10.5 (more )
Note: Confocal Z-projection. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS17: umbilical artery embryonic part Present Regionally restricted 8Biii Expression is in hematopoietic clusters.
Specimen 8C: embryonic day 10.5 (more )
Note: Confocal Z-projection. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Present Regionally restricted 8Ciii Expression is in hematopoietic clusters.
Specimen 8D: embryonic day 10.5 (more )
Note: Confocal Z-projection. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Present Regionally restricted 8Diii Expression is in hematopoietic clusters.
Specimen 9D: embryonic day 10.5 (more )
Note: Confocal Z-projection. Triple labeled: blue - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS17: primitive ventricle Present Clusters 9D Single
Specimen 10A: embryonic day 9.5 (more )
Note: Confocal Z-projection. B: Magnified view of the boxed region in (A). Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS15: blood vessel Present Scattered 10Biii , 10Aiii
TS15: vascular plexus Present Scattered 10Ai , 10Bi Expression is in the cephalic vascular plexus.
TS15: 1st branchial arch maxillary component Present Single cells 10Bi , 10Ai
TS15: future midbrain Present Single cells 10Bi , 10Ai
Specimen 10C: embryonic day 10.0 (more )
Note: Confocal Z-projection. D: Magnified view of the boxed region in (C). Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS16: vascular plexus Present Regionally restricted 10Diii , 10Di , 10Ci , 10Ciii Expression is in cells located at the periphery of the cephalic plexus.
TS16: 1st branchial arch maxillary component Present Single cells 10Di , 10Ciii , 10Diii , 10Ci
TS16: future midbrain Present Single cells 10Di , 10Ciii , 10Diii , 10Ci
Specimen 10E: embryonic day 10.5 (more )
Note: Confocal Z-projection. Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS17: vascular plexus Present Regionally restricted 10Ei , 10Fiii , 10Eiii Expression is in small clusters located at the periphery of the cephalic plexus.
TS17: 1st branchial arch maxillary component Present Single cells 10Eiii , 10Fiii , 10Fi
TS17: midbrain Present Single cells 10Eiii , 10Fiii , 10Fi
Specimen 10G: embryonic day 10.5 (more )
Note: Confocal Z-projection. H: Magnified view of boxed region in (G). Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS17: vascular plexus Present Regionally restricted 10Hi , 10Gi , 10Hiii Expression is in the cephalic vascular plexus.
TS17: carotid artery Present Regionally restricted 10Gi , 10Hiii
TS17: internal carotid artery Absent 10Gi , 10Hiii
Specimen 11A: embryonic day 10.5 (more )
Note: Confocal Z-projection. B: Magnified view of the hematopoietic cluster shown in (A). Triple labeled: green - Kit; red - Pecam1 (assay MGI:6117749); white - Runx1 (assay MGI:6117870).
Structure Level Pattern Image Note
TS17: intersomitic blood vessel Present Regionally restricted 11Biii , 11Aiii Expression is in hematopietic clusters.
TS17: blood vessel Present Regionally restricted 11Biii , 11Aiii Expression is in hematopietic clusters in the dorsal longitudinal anastomotic vessel.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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