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Gene Expression Data
Assay Details
Assay
Reference: J:87368 Raetzman LT, et al., Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression. Dev Biol. 2004 Jan 15;265(2):329-40
Assay type: RNA in situ
MGI Accession ID: MGI:6117449
Gene symbol: Notch3
Gene name: notch 3
Probe: Notch3 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1I: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: adenohypophysis pars anterior Present Widespread 1I Expression enriched in progenitor cells. Authors report expression in most progenitor cells at 12.5 dpc.

Specimen 1J: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: adenohypophysis pars anterior Present Regionally restricted 1J Expression restricted to a subset of progenitor cells at 14.5 dpc.
TS22: remnant of Rathke's pouch Strong Regionally restricted 1J Highest expression in peri-luminal progenitor cells.

Specimen 3A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pituitary gland Present 3A Authors report similar levels of expression in pituitaries of each genotype.

Specimen 3B: embryonic day 12.5; Prop1df/Prop1df (more )
Structure Level Pattern Image Note
TS20: pituitary gland Present 3B Authors report similar levels of expression in pituitaries of each genotype.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory