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Gene Expression Data
Assay Details
Assay
Reference: J:208718 Selmi-Ruby S, et al., The targeted inactivation of TRbeta gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production. Endocrinology. 2014 Feb;155(2):635-46
Assay type: RT-PCR
MGI Accession ID: MGI:6114696
Gene symbol: Dio2
Gene name: deiodinase, iodothyronine, type II
Probe: Dio2-pC, Dio2-pD
Assay notes: Expression levels were assayed using real-time PCR; L32 ribosomal protein mRNA was used as the standard.
Results Image: 7_DIO2
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Amount Genetic BackgroundMutant Allele(s)Sex Note
Thyr-TRB+/+ P m 2 TS28: thyroid gland Present Not Specified; total RNA involves: 129 * C57BL/6 Male
Thyr-TRB+/- P m 2 TS28: thyroid gland Present Not Specified; total RNA involves: 129/Sv * C57BL/6 Thrbtm1Mkni/Thrb+, Hprt1tm1(TG-cre)1Sasr/YMale Conditional mutant.
Thyr-TRB-/- P m 2 TS28: thyroid gland Present Not Specified; total RNA involves: 129/Sv * C57BL/6 Thrbtm1Mkni/Thrbtm1Mkni, Hprt1tm1(TG-cre)1Sasr/YMale Conditional mutant.
Notes:
(a) Expression levels are decreased 2.5-fold in the mutant relative to wild type.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory