Gene Expression Data
Assay Details
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Assay
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Reference:
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J:108385
Cormier S, et al., The murine ortholog of notchless, a direct regulator of the notch pathway in Drosophila melanogaster, is essential for survival of inner cell mass cells. Mol Cell Biol. 2006 May;26(9):3541-9
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:6108335
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Gene symbol:
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Nle1
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Gene name:
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notchless homolog 1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
5A:
embryonic day 1.5; Nle1tm1Cba/Nle1 +
(more  )
Specimen
5A:
(close  )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * SJL/J
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Mutant Allele(s):
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Nle1tm1Cba/Nle1+
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Age:
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embryonic day 1.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS2: 2-cell stage embryo |
Present |
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5A
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Authors report zygotic transcription occured at the two-cell stage.
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Specimen
5B:
embryonic day 3.5; Nle1tm1Cba/Nle1 +
(more )
Specimen
5B:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * SJL/J
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Mutant Allele(s):
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Nle1tm1Cba/Nle1+
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Age:
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embryonic day 3.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS4: inner cell mass |
Present |
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5B
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Expression more intense in the inner cell mass than in the trophectoderm.
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Specimen
5C:
embryonic day 7.5; Nle1tm1Cba/Nle1 +
(more )
Note: Late bud stage.
Specimen
5C:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * SJL/J
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Mutant Allele(s):
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Nle1tm1Cba/Nle1+
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Age:
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embryonic day 7.5
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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Late bud stage.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: embryo |
Present |
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5C
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Expressing cells mainly in embryonic tissue derived from the inner cell mass.
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Analysis Tools