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Gene Expression Data
Assay Details
Assay
Reference: J:240500 Lopez-Domenech G, et al., Loss of Dendritic Complexity Precedes Neurodegeneration in a Mouse Model with Disrupted Mitochondrial Distribution in Mature Dendrites. Cell Rep. 2016 Oct 04;17(2):317-327
Assay type: Western blot
MGI Accession ID: MGI:5906596
Gene symbol: Rhot2
Gene name: ras homolog family member T2
Antibody: anti-Miro2
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: Antibody specific for Miro2 (Rhot2; 74 kDa). Both genes have been annotated.
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure 74 kDa Genetic BackgroundMutant Allele(s)Sex Note
WT P m 12 TS28: brain Weak (a) involves: C57BL/6Dnk * C57BL/6N * FVB/N Rhot1tm1c(EUCOMM)Wtsi/Rhot1tm1c(EUCOMM)WtsiNot Specified
WT P m 12 TS28: brain Weak (a) involves: C57BL/6Dnk * C57BL/6N * FVB/N Rhot1tm1c(EUCOMM)Wtsi/Rhot1tm1c(EUCOMM)WtsiNot Specified
WT P m 12 TS28: brain Weak (a) involves: C57BL/6Dnk * C57BL/6N * FVB/N Rhot1tm1c(EUCOMM)Wtsi/Rhot1tm1c(EUCOMM)WtsiNot Specified
WT P m 12 TS28: brain Weak (a) involves: C57BL/6Dnk * C57BL/6N * FVB/N Rhot1tm1c(EUCOMM)Wtsi/Rhot1tm1c(EUCOMM)WtsiNot Specified
Miro1cko P m 12 TS28: brain Strong (b) involves: C57BL/6Dnk * C57BL/6N * FVB/N Rhot1tm1c(EUCOMM)Wtsi/Rhot1tm1c(EUCOMM)Wtsi, Tg(Camk2a-cre)1Gsc/0Not Specified Conditional mutant.
Miro1cko P m 12 TS28: brain Strong (b) involves: C57BL/6Dnk * C57BL/6N * FVB/N Rhot1tm1c(EUCOMM)Wtsi/Rhot1tm1c(EUCOMM)Wtsi, Tg(Camk2a-cre)1Gsc/0Not Specified Conditional mutant.
Miro1cko P m 12 TS28: brain Strong (b) involves: C57BL/6Dnk * C57BL/6N * FVB/N Rhot1tm1c(EUCOMM)Wtsi/Rhot1tm1c(EUCOMM)Wtsi, Tg(Camk2a-cre)1Gsc/0Not Specified Conditional mutant.
Miro1cko P m 12 TS28: brain Strong (b) involves: C57BL/6Dnk * C57BL/6N * FVB/N Rhot1tm1c(EUCOMM)Wtsi/Rhot1tm1c(EUCOMM)Wtsi, Tg(Camk2a-cre)1Gsc/0Not Specified Conditional mutant.
Miro2ko P m 12 TS28: brain Absent involves: C57BL/6N * C57BL/6NTac Rhot2tm1(KOMP)Wtsi/Rhot2tm1(KOMP)WtsiNot Specified
Miro2ko P m 12 TS28: brain Absent involves: C57BL/6N * C57BL/6NTac Rhot2tm1(KOMP)Wtsi/Rhot2tm1(KOMP)WtsiNot Specified
Miro2ko P m 12 TS28: brain Absent involves: C57BL/6N * C57BL/6NTac Rhot2tm1(KOMP)Wtsi/Rhot2tm1(KOMP)WtsiNot Specified
Miro2ko P m 12 TS28: brain Absent involves: C57BL/6N * C57BL/6NTac Rhot2tm1(KOMP)Wtsi/Rhot2tm1(KOMP)WtsiNot Specified
Notes:
(a) Authors report that expression levels decreased progressively over time in wild type animals.
(b) Expression levels increase after Miro1 (Rhot1) deletion.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory