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Gene Expression Data
Assay Details
Assay
Reference: J:181634 Wallgard E, et al., Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development. Dev Dyn. 2012 Apr;241(4):770-86
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5904514
Gene symbol: Pald1
Gene name: phosphatase domain containing, paladin 1
Antibody: anti-PALD1
Detection system: Alexa Fluor 568
Results
Specimen 3l: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain blood vessel Strong Regionally restricted 3l Strong expression in brain capillaries.
Specimen 3m: embryonic day 14.5 (more )
Note: Double labeled: red - Pald1 protein; green - isolectin B4.
Structure Level Pattern Image Note
TS22: atrium cardiac muscle Present 3m
Specimen 3n: embryonic day 14.5 (more )
Note: Double labeled: red - Pald1 protein; green - isolectin B4.
Structure Level Pattern Image Note
TS22: ventricle cardiac muscle Present 3n
Specimen 3o: embryonic day 14.5 (more )
Note: Double labeled: red - Pald1 protein; blue - Hoechst staining.
Structure Level Pattern Image Note
TS22: lung mesenchyme Present 3o
Specimen 3p: embryonic day 14.5 (more )
Note: Double labeled: red - Pald1 protein; blue - Hoechst staining.
Structure Level Pattern Image Note
TS22: maturing glomerular tuft Present 3p
TS22: mesenchyme of metanephros Present 3p
Specimen 5a: embryonic day 14.5; Efnb2tm2Sor/Efnb2+ (more )
Note: Triple labeled: red - Pald1 protein; green - Efnb2 reporter (assay MGI:5904503); blue - Hoechst staining.
Structure Level Pattern Image Note
TS22: vena cava Strong Regionally restricted 5a Strong expression in endothelial cells of vena cava.
TS22: dorsal aorta Weak Regionally restricted 5a Weak expression in aortic vascular smooth muscle cells (vSMC).
Specimen 5b: embryonic day 14.5; Efnb2tm2Sor/Efnb2+ (more )
Note: Triple labeled: red - Pald1 protein; green - Efnb2 reporter (assay MGI:5904503); blue - Hoechst staining.
Structure Level Pattern Image Note
TS22: intercostal artery Present 5b
TS22: intercostal vein Present 5b
Specimen 6c: embryonic day 14.5 (more )
Note: Double labeled: red - Pald1 protein; green - isolectin B4.
Structure Level Pattern Image Note
TS22: central nervous system vascular element Present Regionally restricted 6c Authors report expression overlaps endothelial markers.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory