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Gene Expression Data
Assay Details
Assay
Reference: J:181634 Wallgard E, et al., Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development. Dev Dyn. 2012 Apr;241(4):770-86
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5904503
Gene symbol: Efnb2
Gene name: ephrin B2
Reporter: GFP
Antibody: anti-GFP
Results
Specimen 5a: embryonic day 14.5; Efnb2tm2Sor/Efnb2+ (more )
Note: Triple labeled: green - Efnb2 reporter; red - Pald1 protein (assay MGI:5904514); blue - Hoechst staining.
Structure Level Pattern Image Note
TS22: arterial blood vessel Strong Regionally restricted 5a Strong expression in arterial endothelial cells of aorta and intercostal blood vessels.
TS22: vena cava Strong Regionally restricted 5a Highly expressed in endothelial cells of vena cava.
TS22: dorsal aorta Weak Regionally restricted 5a Lower degree of expression in aortic endothelial cells. Weak expression in aortic vascular smooth muscle cells.
Specimen 5b: embryonic day 14.5; Efnb2tm2Sor/Efnb2+ (more )
Note: Triple labeled: green - Efnb2 reporter; red - Pald1 protein (assay MGI:5904514); blue - Hoechst staining.
Structure Level Pattern Image Note
TS22: intercostal artery Present 5b
TS22: intercostal vein Present 5b
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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