Gene Expression Data
Assay Details
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Assay
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Reference:
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J:210785
Lee SI, et al., A null mutation of mouse Kcna10 causes significant vestibular and mild hearing dysfunction. Hear Res. 2013 Jun;300:1-9
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5902041
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Gene symbol:
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Kcna10
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Gene name:
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potassium voltage-gated channel, shaker-related subfamily, member 10
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
E18.5 apical:
(close  )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: organ of Corti |
Weak |
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2_row 1 left
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Expressed in few individual inner hair cells.
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Specimen
E18.5 middle:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: organ of Corti |
Present |
Regionally restricted |
2_row 1 middle
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Expression gradually diminishes toward the middle turn from the basal turn in the inner hair cells.
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Specimen
E18.5 upper basal:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: organ of Corti |
Present |
Regionally restricted |
2_row 1 right
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Strongest expression in the inner hair cells.
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Specimen
E18.5 organ of Corti:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: organ of Corti |
Present |
Graded |
2_row 2 left
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Expressed in the inner hair cells in a tonotopic gradient, with the strongest expression at the basal turn.
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Specimen
E18.5 utricle and ampullare:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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Specimen
E18.5 saccule:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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Specimen
P17 apical:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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postnatal day 17
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
2_row 3 left
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Even expression in the inner hair cells. Lesser expression in outer hair cells. Expression in outer hair cells is strongest at the apical turn.
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Specimen
P17 middle:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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postnatal day 17
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
2_row 3 middle
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Even expression in the inner hair cells. Lesser expression in outer hair cells.
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Specimen
P17 upper basal:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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postnatal day 17
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
2_row 3 right
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Even expression in the inner hair cells. Faint expression in the outer hair cells is discernable at the basal turn.
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Specimen
P17 organ of Corti:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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postnatal day 17
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
2_row 4 left
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Even expression in the inner hair cells. Expression in outer hair cells is strongest at the apical turn and faint expression is discernable at the basal turn.
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Specimen
P17 utricle and ampullare:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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postnatal day 17
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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Specimen
P17 saccule:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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postnatal day 17
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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Specimen
P75 apical:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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postnatal day 75
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
2_row 5 left
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Even expression in the inner hair cells. Lesser expression in outer hair cells. Expression in outer hair cells is strongest at the apical turn.
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Specimen
P75 middle:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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postnatal day 75
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
2_row 5 middle
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Even expression in the inner hair cells. Lesser expression in outer hair cells.
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Specimen
P75 upper basal:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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postnatal day 75
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
2_row 5 right
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Even expression in the inner hair cells. Faint expression in the outer hair cells is discernable at the basal turn.
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Specimen
P75 organ of Corti:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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postnatal day 75
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
2_row 6 left
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Even expression in the inner hair cells. Expression in outer hair cells is strongest at the apical turn and faint expression is discernable at the basal turn.
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Specimen
P75 utricle and ampullare:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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postnatal day 75
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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Specimen
P75 saccule:
(close )
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Genetic Background:
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involves: 129S/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Kcna10tm1Lex/Kcna10tm1Lex
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Age:
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postnatal day 75
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Sex:
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Not Specified
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Type:
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Not Specified
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Fixation:
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2% Paraformaldehyde
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Analysis Tools
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