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Kcna10tm1Lex
Targeted Allele Detail
Summary
Symbol: Kcna10tm1Lex
Name: potassium voltage-gated channel, shaker-related subfamily, member 10; targeted mutation 1, Lexicon Genomics
MGI ID: MGI:5574085
Synonyms: Kcna10TM45
Gene: Kcna10  Location: Chr3:107090459-107103037 bp, + strand  Genetic Position: Chr3, 46.64 cM
Alliance: Kcna10tm1Lex page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:210785
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEvBrd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
    A IRES-beta-geo and puromycin resistance cassette replaced exon 2, the entire coding sequence. (J:210785)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 23 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcna10 Mutation:  26 strains or lines available
References
Original:  J:210785 Lee SI, et al., A null mutation of mouse Kcna10 causes significant vestibular and mild hearing dysfunction. Hear Res. 2013 Jun;300:1-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory