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Gene Expression Data
Assay Details
Assay
Reference: J:152922 Golson ML, et al., Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5827907
Gene symbol: Ins2
Gene name: insulin II
Antibody: anti-Insulin
Detection system: Cy2
Results
Specimen 3A: postnatal day 21; Jag1tm1.1Loo/Jag1tm1.1Loo (more )
Note: Authors state that littermate Jag1loxP/loxP and Jag1loxP/+ mice were used as controls in most experiments. Double labeled: green - Ins1 and Ins2; red - Gluc (Gcg assay MGI:5827902).
Structure Level Pattern Image Note
TS28: pancreas parenchyma Present Regionally restricted 3A
Specimen 3B: postnatal day 21; Jag1tm1.1Loo/Jag1tm1.1Loo, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant. Double labeled: green - Ins1 and Ins2; red - Gluc (Gcg assay MGI:5827902).
Structure Level Pattern Image Note
TS28: pancreas parenchyma Present Regionally restricted 3B Authors report no change in beta-cell mass in mutants vs. controls.
Specimen 3C: postnatal day 21; Jag1tm1.1Loo/Jag1tm1.1Loo (more )
Note: Authors state that littermate Jag1loxP/loxP and Jag1loxP/+ mice were used as controls in most experiments. Double labeled: green - Ins1 and Ins2; red - Sst (assay MGI:5827908).
Structure Level Pattern Image Note
TS28: pancreas parenchyma Present Regionally restricted 3C
Specimen 3D: postnatal day 21; Jag1tm1.1Loo/Jag1tm1.1Loo, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant. Double labeled: green - Ins1 and Ins2; red - Sst (assay MGI:5827908).
Structure Level Pattern Image Note
TS28: pancreas parenchyma Present Regionally restricted 3D Authors report no change in beta-cell mass in mutants vs. controls.
Specimen 3E: postnatal day 21; Jag1tm1.1Loo/Jag1tm1.1Loo (more )
Note: Authors state that littermate Jag1loxP/loxP and Jag1loxP/+ mice were used as controls in most experiments. Double labeled: green - Ins1 and Ins2; red - PP (Ppy assay MGI:5827912).
Structure Level Pattern Image Note
TS28: pancreas parenchyma Present Regionally restricted 3E
Specimen 3F: postnatal day 21; Jag1tm1.1Loo/Jag1tm1.1Loo, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant. Double labeled: green - Ins1 and Ins2; red - PP (Ppy assay MGI:5827912).
Structure Level Pattern Image Note
TS28: pancreas parenchyma Present Regionally restricted 3F Authors report no change in beta-cell mass in mutants vs. controls.
Specimen 6E: embryonic day 16.5; Jag1tm1.1Loo/Jag1tm1.1Loo (more )
Note: Authors state that littermate Jag1loxP/loxP and Jag1loxP/+ mice were used as controls in most experiments. Double labeled: green - Ins1 and Ins2; red - Gluc (Gcg assay MGI:5827902).
Structure Level Pattern Image Note
TS24: pancreas parenchyma Present Regionally restricted 6E
Specimen 6F: embryonic day 16.5; Jag1tm1.1Loo/Jag1tm1.1Loo, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant. Double labeled: green - Ins1 and Ins2; red - Gluc (Gcg assay MGI:5827902).
Structure Level Pattern Image Note
TS24: pancreas parenchyma Present Regionally restricted 6F Authors report that the number of endocrine precursors was reduced by approximately one-half.
Specimen E18.5 Control not shown: embryonic day 18.5; Jag1tm1.1Loo/Jag1tm1.1Loo (more )
Note: Authors state that littermate Jag1loxP/loxP and Jag1loxP/+ mice were used as controls in most experiments.
Structure Level Pattern Image Note
TS26: pancreas parenchyma Present
Specimen E18.5 Mutant not shown: embryonic day 18.5; Jag1tm1.1Loo/Jag1tm1.1Loo, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: pancreas parenchyma Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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