About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:152922 Golson ML, et al., Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5827908
Gene symbol: Sst
Gene name: somatostatin
Results
Specimen E16.5 not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: endocrine pancreas Present Regionally restricted Expression in differentiated endocrine cells.
Specimen 3C: postnatal day 21; Jag1tm1.1Loo/Jag1tm1.1Loo (more )
Note: Authors state that littermate Jag1loxP/loxP and Jag1loxP/+ mice were used as controls in most experiments. Double labeled: red - Sst; green - Ins1 (assay MGI:5827906) and Ins2 (assay MGI:5827907).
Structure Level Pattern Image Note
TS28: pancreas parenchyma Present Regionally restricted 3C
Specimen 3D: postnatal day 21; Jag1tm1.1Loo/Jag1tm1.1Loo, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant. Double labeled: red - Sst; green - Ins1 (assay MGI:5827906) and Ins2 (assay MGI:5827907).
Structure Level Pattern Image Note
TS28: pancreas parenchyma Strong Regionally restricted 3D Authors report an approximate 2.5-fold incerase in alpha-cell mass by P21 in mutants vs. controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory