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Gene Expression Data
Assay Details
Assay
Reference: J:36300 Millauer B, et al., High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell. 1993 Mar 26;72(6):835-46
Assay type: RNA in situ
MGI Accession ID: MGI:5825105
Gene symbol: Kdr
Gene name: kinase insert domain protein receptor
Probe: flk-1 probe4
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 3A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: heart ventricle Strong 3A
TS22: lung Strong 3A
TS22: meninges Strong 3A
TS22: brain Present 3A
TS22: liver Present 3A
TS22: mandible Present 3A
TS22: axial skeleton Present Regionally restricted 3A Thin strands of expression in intersegmental regions of vertebra.
TS22: dorsal aorta Present Regionally restricted 3A Expression at inner surface of atrium and aorta.
TS22: heart atrium Present Regionally restricted 3A Expression at inner surface of atrium and aorta.

Specimen 3B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: dorsal aorta Present Regionally restricted 3B Expression in endothelial cells of wall of aorta. No expression in muscular layer.

Specimen 3D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung vascular element Present Regionally restricted 3D Expression in structures likely representing peribronchial capillaries.

Specimen 3F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: bronchus epithelium Absent 3F

Specimen 3H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: heart blood vessel Present Regionally restricted 3H Expression in presumptive ventricular capillaries.
TS22: atrium endocardial lining Present 3H

Specimen 4A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: blood vessel Strong Regionally restricted 4A High expression in perineural vascular plexus and in structures resembling invading vascular sprouts.

Specimen 4B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain blood vessel Strong Regionally restricted 4B Large amounts of expression in numerous radial vessels as well as branching vessels of the intraneural plexus.

Specimen 4C: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: brain blood vessel Strong Regionally restricted 4C Strong expression in vessels of intraneural plexus.

Specimen 4D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: midbrain Weak 4D Very low expression in brain.
TS28: choroid plexus Present 4D Expression restricted mainly to choroid plexus.

Specimen 4E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: choroid plexus stroma Present Regionally restricted 4E Expression in cells of inner vascular layer.
TS28: choroid plexus epithelium Absent 4E

Specimen 4F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: choroid plexus stroma Present Regionally restricted 4F Expression in cells of inner vascular layer.
TS28: choroid plexus epithelium Absent 4F

Specimen 6A maternal: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted 6A Expression in maternal blood vessels in decidua.

Specimen 6A embryonic: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: allantois Present 6A
TS13: trophectoderm Present 6A
TS13: yolk sac Present 6A
TS13: embryo mesenchyme Present 6A

Specimen 6B maternal: postnatal adult (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Strong Regionally restricted 6B In decidua, high levels of expression in inner lining of blood vessels.

Specimen 6C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: yolk sac mesenchyme Present 6C Expression confined to mesodermal layer, where hemangioblast differentiate.
TS15: trophectoderm Present 6C

Specimen 6D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: yolk sac mesenchyme Present Regionally restricted 6D Expression in peripheral angioblasts in blood islands.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory