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Lcp1tm1Shcm
Targeted Allele Detail
Summary
Symbol: Lcp1tm1Shcm
Name: lymphocyte cytosolic protein 1; targeted mutation 1, Sharon Celeste Morley
MGI ID: MGI:5824109
Synonyms: LPLfl
Gene: Lcp1  Location: Chr14:75368570-75468282 bp, + strand  Genetic Position: Chr14, 39.63 cM
Alliance: Lcp1tm1Shcm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:238746
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted into intron 1 and an FRT site flanked neomycin resistance gene cassette plus a second loxP site were inserted into intron 2. (J:238746)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lcp1 Mutation:  41 strains or lines available
References
Original:  J:238746 Todd EM, et al., Alveolar macrophage development in mice requires L-plastin for cellular localization in alveoli. Blood. 2016 Dec 15;128(24):2785-2796
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory