Gene Expression Data
Assay Details
Assay
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Reference:
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J:16077
Schneider-Maunoury S, et al., Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain. Cell. 1993 Dec 17;75(6):1199-214
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5823215
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Gene symbol:
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Egr2
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Gene name:
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early growth response 2
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
2A:
embryonic day 8.0; Egr2tm1Pch/Egr2 +
(more )
Note: 0-3 somites
Specimen
2A:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2+
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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0-3 somites
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Specimen
2B:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2tm1Pch
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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0-3 somites
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Specimen
2C:
embryonic day 9.0; Egr2tm1Pch/Egr2 +
(more )
Note: 10-13 somites
Specimen
2C:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2+
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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10-13 somites
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Specimen
2D:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2tm1Pch
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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10-13 somites
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Specimen
2E:
embryonic day 9.5; Egr2tm1Pch/Egr2 +
(more )
Specimen
2E:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
2F:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2tm1Pch
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
2G:
embryonic day 10.5; Egr2tm1Pch/Egr2 +
(more )
Specimen
2G:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS17: cranial ganglion |
Present |
Regionally restricted |
2G
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Expression is at the boundary gap cells.
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TS17: spinal nerve |
Present |
Regionally restricted |
2G
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Expression is in sensory and motor roots of spinal nerves and in the portion of nerve XI in close proximity to the central nervous system.
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TS17: rhombomere 5 |
Trace |
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2G
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Specimen
2H:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2tm1Pch
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS17: acoustic ganglion |
Present |
Regionally restricted |
2H
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Expression is at the nearly fused boundary gap cells of nerves V and VII/VIII.
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TS17: facial ganglion |
Present |
Regionally restricted |
2H
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Expression is at the nearly fused boundary gap cells of nerves V and VII/VIII.
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TS17: trigeminal ganglion |
Present |
Regionally restricted |
2H
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Expression is at the nearly fused boundary gap cells of nerves V and VII/VIII.
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TS17: spinal nerve |
Present |
Regionally restricted |
2H
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Expression is in motor roots of spinal nerves and in the portion of nerve XI in close proximity to the central nervous system.
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Specimen
3A:
embryonic day 8.5; Egr2tm1Pch/Egr2 +
(more )
Specimen
3A:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2+
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS13: migrating neural crest |
Present |
Regionally restricted |
3A
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Expression is in a population of cells posterior to rhombomere 5 that corresponds to migrating neural crest cells into the third branchial arch.
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TS13: anterior pro-rhombomere |
Present |
Regionally restricted |
3A
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Expression is in rhombomere 3 and 5.
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Specimen
3B:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2tm1Pch
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS13: migrating neural crest |
Present |
Regionally restricted |
3B
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Expression is in a population of cells anterior and posterior to rhombomere 5, the latter corresponds to migrating neural crest cells into the third branchial arch.
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TS13: anterior pro-rhombomere |
Present |
Regionally restricted |
3B
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Expression is in rhombomere 5.
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Specimen
3C:
embryonic day 9.5; Egr2tm1Pch/Egr2 +
(more )
Specimen
3C:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
3D:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2tm1Pch
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS15: rhombomere 5 |
Weak |
Regionally restricted |
3D
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Expression is in a small area adjacent to the rostral part of the otic vesicle.
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Specimen
3E:
embryonic day 10.5; Egr2tm1Pch/Egr2 +
(more )
Specimen
3E:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
3F:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2tm1Pch
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS17: acoustic ganglion |
Present |
Regionally restricted |
3F
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Expression is in the nerve plexus that corresponds to a fusion of these ganglia.
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TS17: facial ganglion |
Present |
Regionally restricted |
3F
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Expression is in the nerve plexus that corresponds to a fusion of these ganglia.
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TS17: trigeminal ganglion |
Present |
Regionally restricted |
3F
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Expression is in the nerve plexus that corresponds to a fusion of these ganglia.
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TS17: hindbrain |
Absent |
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3F
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Specimen
5A:
embryonic day 11.5; Egr2tm1Pch/Egr2 +
(more )
Specimen
5A:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
5B:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2tm1Pch
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS19: acoustic ganglion |
Present |
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5B
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There are changes in morphology in cranial nerves and ganglia in this mutant.
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TS19: cranial nerve |
Present |
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5B
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There are changes in morphology in cranial nerves and ganglia in this mutant.
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TS19: facial ganglion |
Present |
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5B
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There are changes in morphology in cranial nerves and ganglia in this mutant.
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TS19: trigeminal ganglion |
Present |
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5B
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There are changes in morphology in cranial nerves and ganglia in this mutant.
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Specimen
5C:
embryonic day 11.5; Egr2tm1Pch/Egr2 +
(more )
Specimen
5C:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
5D:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2tm1Pch
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS19: cranial ganglion |
Present |
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5D
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There are changes in morphology in cranial nerves and ganglia in this mutant.
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TS19: cranial nerve |
Present |
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5D
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There are changes in morphology in cranial nerves and ganglia in this mutant.
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Specimen
7E:
embryonic day 9.0; Egr2tm1Pch/Egr2 +
(more )
Note: 11-13 somites
Specimen
7E:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
|
Egr2tm1Pch/Egr2+
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Age:
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embryonic day 9.0
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Sex:
|
Not Specified
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Type:
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section
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Note:
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11-13 somites
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Specimen
7F:
(close )
Genetic Background:
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involves: 129S2/SvPas * C57BL/6 * DBA/2
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Mutant Allele(s):
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Egr2tm1Pch/Egr2tm1Pch
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Age:
|
embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Note:
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11-13 somites
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