Gene Expression Data
Assay Details
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Assay
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Reference:
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J:153642
Vlangos CN, et al., Caudal regression in adrenocortical dysplasia (acd) mice is caused by telomere dysfunction with subsequent p53-dependent apoptosis. Dev Biol. 2009 Oct 15;334(2):418-28
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5817714
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Gene symbol:
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Casp3
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Gene name:
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caspase 3
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Antibody:
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anti-cleaved Caspase3
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to Cy2
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Results
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Specimen
3D:
embryonic day 11.5
(more  )
Specimen
3D:
(close  )
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Genetic Background:
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involves: C57BL/6J * DW/J
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: embryo |
Present |
Regionally restricted |
3D
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Expression is in the caudal region.
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Specimen
3I:
(close )
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Genetic Background:
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involves: C57BL/6J * DW/J
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Mutant Allele(s):
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Acdacd/Acdacd
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: embryo |
Strong |
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3I
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The number of positive cells in the caudal region are increased in this mutant.
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Specimen
E9.5 WT:
embryonic day 9.5
(more )
Note: These data are depicted graphically in Fig. 3K.
Specimen
E9.5 WT:
(close )
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Genetic Background:
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involves: C57BL/6J * DW/J
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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These data are depicted graphically in Fig. 3K.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: embryo |
Present |
Regionally restricted |
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Expression is in the caudal region.
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Specimen
E9.5 mutant:
embryonic day 9.5; Acdacd/ Acdacd
(more )
Note: These data are depicted graphically in Fig. 3K.
Specimen
E9.5 mutant:
(close )
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Genetic Background:
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involves: C57BL/6J * DW/J
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Mutant Allele(s):
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Acdacd/Acdacd
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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These data are depicted graphically in Fig. 3K.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: embryo |
Present |
Regionally restricted |
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The number of positive cells in the caudal region are significantly increased in this mutant.
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Specimen
E10.5 WT:
embryonic day 10.5
(more )
Note: These data are depicted graphically in Fig. 3K.
Specimen
E10.5 WT:
(close )
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Genetic Background:
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involves: C57BL/6J * DW/J
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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These data are depicted graphically in Fig. 3K.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: embryo |
Present |
Regionally restricted |
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Expression is in the caudal region.
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Specimen
E10.5 mutant:
embryonic day 10.5; Acdacd/ Acdacd
(more )
Note: These data are depicted graphically in Fig. 3K.
Specimen
E10.5 mutant:
(close )
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Genetic Background:
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involves: C57BL/6J * DW/J
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Mutant Allele(s):
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Acdacd/Acdacd
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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These data are depicted graphically in Fig. 3K.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: embryo |
Present |
Regionally restricted |
|
The number of positive cells in the caudal region are significantly increased in this mutant.
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Specimen
E11.5 WT:
embryonic day 11.5
(more )
Note: These data are depicted graphically in Fig. 3K.
Specimen
E11.5 WT:
(close )
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Genetic Background:
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involves: C57BL/6J * DW/J
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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These data are depicted graphically in Fig. 3K.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: embryo |
Present |
Regionally restricted |
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Expression is in the caudal region.
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Specimen
E11.5 mutant:
embryonic day 11.5; Acdacd/ Acdacd
(more )
Note: These data are depicted graphically in Fig. 3K.
Specimen
E11.5 mutant:
(close )
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Genetic Background:
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involves: C57BL/6J * DW/J
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Mutant Allele(s):
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Acdacd/Acdacd
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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These data are depicted graphically in Fig. 3K.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: embryo |
Present |
Regionally restricted |
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The number of positive cells in the caudal region are significantly increased in this mutant.
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Specimen
6B:
embryonic day 10.5; Acdacd/Acd +
(more )
Specimen
6B:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6J * DW/J
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Mutant Allele(s):
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Acdacd/Acd+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: embryo |
Present |
Single cells |
6C
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6B
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There is an occasional expressing cell.
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Specimen
6E:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6J * DW/J
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Mutant Allele(s):
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Acdacd/Acdacd
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
6H:
(close )
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Genetic Background:
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involves: 129S2/SvPas * C57BL/6J * DW/J
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Mutant Allele(s):
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Acdacd/Acdacd
Trp53tm1Tyj/Trp53tm1Tyj
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: embryo |
Present |
Single cells |
6I
,
6H
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There is an occasional expressing cell.
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Analysis Tools