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Gene Expression Data
Assay Details
Assay
Reference: J:223384 Abdelhamed ZA, et al., The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway. Dis Model Mech. 2015 Jun;8(6):527-41
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5816839
Gene symbol: Alms1
Gene name: ALMS1, centrosome and basal body associated
Antibody: Anti-Alms1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2F basal Tmem67+/+: postnatal newborn (more )
Note: Confocal image of the basal region. Double labeled: green - Alms1; red - actin.
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 2F basal Tmem67+/+ Expression was detected in ciliary basal bodies.
Specimen 2F basal Tmem67-/-: postnatal newborn; Tmem67tm1Dgen/Tmem67tm1Dgen (more )
Note: Confocal image of the basal region. Double labeled: green - Alms1; red - actin.
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 2F basal Tmem67-/- Expression was detected in ciliary basal bodies.
Specimen 2F apical Tmem67+/+: postnatal newborn (more )
Note: Confocal image of the apical region. Double labeled: green - Alms1; red - actin.
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 2F apical Tmem67+/+ Expression was detected in ciliary basal bodies.
Specimen 2F apical Tmem67-/-: postnatal newborn; Tmem67tm1Dgen/Tmem67tm1Dgen (more )
Note: Confocal image of the apical region. Double labeled: green - Alms1; red - actin.
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 2F apical Tmem67-/- Expression was detected in ciliary basal bodies.
Specimen S2B basal Tmem67+/+: embryonic day 15.5 (more )
Note: Confocal image of the basal region. Double labeled: green - Alms1; red - phalloidin.
Structure Level Pattern Image Note
TS23: cochlea Present Regionally restricted S2B basal Tmem67+/+ Expression was detected in basal bodies in the organ of Corti.
Specimen S2B basal Tmem67-/-: embryonic day 15.5; Tmem67tm1Dgen/Tmem67tm1Dgen (more )
Note: Confocal image of the basal region. Double labeled: green - Alms1; red - phalloidin.
Structure Level Pattern Image Note
TS23: cochlea Present Regionally restricted S2B basal Tmem67-/- Expression was detected in basal bodies in the organ of Corti.
Specimen S2B mid Tmem67+/+: embryonic day 15.5 (more )
Note: Confocal image of the mid region. Double labeled: green - Alms1; red - phalloidin.
Structure Level Pattern Image Note
TS23: cochlea Present Regionally restricted S2B mid Tmem67+/+ Expression was detected in basal bodies in the organ of Corti.
Specimen S2B mid Tmem67-/-: embryonic day 15.5; Tmem67tm1Dgen/Tmem67tm1Dgen (more )
Note: Confocal image of the mid region. Double labeled: green - Alms1; red - phalloidin.
Structure Level Pattern Image Note
TS23: cochlea Present Regionally restricted S2B mid Tmem67-/- Expression was detected in basal bodies in the organ of Corti.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory