About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:195918 Vieux-Rochas M, et al., BMP-mediated functional cooperation between Dlx5;Dlx6 and Msx1;Msx2 during mammalian limb development. PLoS One. 2013;8(1):e51700
Assay type: RT-PCR
MGI Accession ID: MGI:5810626
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Results
Image: S3_Fgf8 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
Msx-/- E11.0 TS18: hindlimb bud Present Not Specified involves: 129P2/OlaHsd * C57BL/6 * DBA Msx1tm1Bero/Msx1tm1BeroNot Specified
Dlx5-/-;Dlx6-/- E11.0 TS18: hindlimb bud Weak (a) Not Specified involves: C57BL/6 * DBA Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi, Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1LeviNot Specified This embryo was a single homozygote. However, since this allele affects two genes, the MGI database schema requires that we need to enter an allele pair per affected gene (thus resulting in the animal looking like a double homozygote).
Msx1+/-;Dlx5+/-;Dlx6+/- E11.0 TS18: hindlimb bud Trace (b) Not Specified involves: 129P2/OlaHsd * C57BL/6 * DBA Dlx5/Dlx6tm1Levi/Dlx5+, Dlx5/Dlx6tm1Levi/Dlx6+, Msx1tm1Bero/Msx1+Not Specified This embryo was a double heterozygote. However, since the Dlx5/6 allele affects two genes, the MGI database schema requires that we need to enter an allele pair per affected gene (thus resulting in the animal looking like a triple heterozygote).
Msx1+/-;Dlx5-/-;Dlx6-/- E11.0 TS18: hindlimb bud Trace (b) Not Specified involves: 129P2/OlaHsd * C57BL/6 * DBA Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi, Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi, Msx1tm1Bero/Msx1+Not Specified This embryo was a single homozygote for the Dl5/6 allele. However, since that allele affects two genes, the MGI database schema requires that we need to enter an allele pair per affected gene (thus resulting in the animal looking like a double homozygote).
Notes:
(a) Expression slightly reduced compared to wildtype.
(b) Expression drastically reduced compared to wildtype.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory