About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:55154 Schwarz M, et al., Pax2/5 and Pax6 subdivide the early neural tube into three domains. Mech Dev. 1999 Apr;82(1-2):29-39
Assay type: RNA in situ
MGI Accession ID: MGI:5810326
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Probe: Otx2 cDNA1
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 4bA/C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS22: tectum Present 4bC , 4bA
TS22: midbrain tegmentum Present 4bA , 4bC Expression was detected in the midbrain tegmentum up to the fovea isthmus.
TS22: 4th ventricle choroid plexus Present 4bC , 4bA
TS22: cerebellum Absent 4bA , 4bC Appeared as a gap in the expression domains.
TS22: pons Absent 4bA , 4bC Appeared as a gap in the expression domains.
Specimen 4bB/D: embryonic day 13.5; Pax2tm1Pgr/Pax2tm1Pgr, Pax5tm1Mbu/Pax5tm1Mbu (more )
Structure Level Pattern Image Note
TS22: hindbrain alar plate Present Regionally restricted 4bB , 4bD Expression was found in a continuous territory up to the choroid plexus of the fourth ventricle with no gap of expression due to the loss of tissue in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory