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Gene Expression Data
Assay Details
Assay
Reference: J:154075 Weatherbee SD, et al., A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling. Hum Mol Genet. 2009 Dec 1;18(23):4565-75
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5805446
Gene symbol: Nkx2-2
Gene name: NK2 homeobox 2
Antibody: 74.5A5
Results
Specimen 6c: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 6c Expression is in V3 interneurons.
Specimen 6g: embryonic day 10.5; Mks1krc/Mks1krc (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present 6g The expressing V3 interneuron domain is reduced in this mutant.
Specimen 6k: embryonic day 10.5; Ptch1tm1Mps/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 6k The expression domain has expanded in this mutant.
Specimen 6o: embryonic day 10.5; Mks1krc/Mks1krc, Ptch1tm1Mps/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Single cells 6o Expression is in fewer V3 interneurons.
Specimen 6s: embryonic day 10.5; Smotm1Amc/Smotm1Amc (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Absent 6s
Specimen 6w: embryonic day 10.5; Mks1krc/Mks1krc, Smotm1Amc/Smotm1Amc (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Absent 6w
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory