Bmp7tm1.1(cre/ERT2)Grsh
Targeted Allele Detail
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Symbol: |
Bmp7tm1.1(cre/ERT2)Grsh |
Name: |
bone morphogenetic protein 7; targeted mutation 1.1, Irina Grishina |
MGI ID: |
MGI:5792123 |
Synonyms: |
Bmp7-CreERT2 |
Gene: |
Bmp7 Location: Chr2:172709805-172782114 bp, - strand Genetic Position: Chr2, 95.54 cM
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Alliance: |
Bmp7tm1.1(cre/ERT2)Grsh page
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Germline Transmission: |
Earliest citation of germline transmission:
J:101977
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6N
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Allele Type: |
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Targeted (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Bmp7tm1.1(cre/ERT2)Grsh expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: A targeting construct was designed to replace exon 1, including the translation start, of the bone morphogenetic protein 7 (Bmp7) gene with a creER fusion gene (a Cre recombinase fused to a human estrogen receptor ligand binding domain). The Cre/ER sequence is followed by a hGHpA cassette (human Growth Hormone polyadenylation signal) and a frt-flanked puromycin resistance (puro) cassette. The chimeric mice were bred to mice expressing FLP Recombinase to remove puro cassette.
(J:101977)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Bmp7
(mouse)
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Original: |
J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017; |
All: |
1 reference(s) |
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