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Gene Expression Data
Assay Details
Assay
Reference: J:153908 de Castro BM, et al., The vesicular acetylcholine transporter is required for neuromuscular development and function. Mol Cell Biol. 2009 Oct;29(19):5238-50
Assay type: Western blot
MGI Accession ID: MGI:5788316
Gene symbol: Syp
Gene name: synaptophysin
Results Image: 2B Synaptophysin
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex Note
wt/wt E18.5 TS26: spinal cord Present Not Specified Not Specified
wt/del E18.5 TS26: spinal cord Present involves: 129S4/SvJae * C57BL/6J Chat/Slc18a3tm1.1Vpra/Chat+, Chat/Slc18a3tm1.1Vpra/Slc18a3+Not Specified This embryo was a single heterozygote. However, since this allele affects two genes, the MGI database schema requires that we need to enter an allele pair per affected gene (thus resulting in the animal looking like a double heterozygote).
del/del E18.5 TS26: spinal cord Present (a) involves: 129S4/SvJae * C57BL/6J Chat/Slc18a3tm1.1Vpra/Chat/Slc18a3tm1.1Vpra, Chat/Slc18a3tm1.1Vpra/Chat/Slc18a3tm1.1VpraNot Specified This embryo was a single homozygote. However, since this allele affects two genes, the MGI database schema requires that we need to enter an allele pair per affected gene (thus resulting in the animal looking like a double homozygote).
Notes:
(a) The expression level was unchanged in the del/del mice.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory