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Gene Expression Data
Assay Details
Assay
Reference: J:151303 Burdon KP, et al., Mutations in a novel gene, NHS, cause the pleiotropic effects of Nance-Horan syndrome, including severe congenital cataract, dental anomalies, and mental retardation. Am J Hum Genet. 2003 Nov;73(5):1120-30
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5788313
Gene symbol: Nhs
Gene name: NHS actin remodeling regulator
Reporter: lacZ
Direct Detection
Results
Specimen 4A: embryonic day 10.5; NhsGt(414)Pgr/Nhs+ (more )
Structure Level Pattern Image Note
TS17: hindbrain Strong Regionally restricted 4A Expression is in the ventral1.
TS17: midbrain Strong Regionally restricted 4A Expression is in the ventral1.
TS17: neural tube Strong Regionally restricted 4A Expression is in the ventral1.
TS17: heart Present 4A
Specimen 4B: embryonic day 11.5; NhsGt(414)Pgr/Nhs+ (more )
Structure Level Pattern Image Note
TS19: olfactory epithelium Strong 4B
TS19: apical ectodermal ridge Present 4B
TS19: heart Present 4B
TS19: lens vesicle Present 4B
TS19: maxillary process Present Regionally restricted 4B Expression is ventral.
TS19: mandibular process Present Regionally restricted 4B Expression is dorsal.
Specimen 4C: embryonic day 12.5; NhsGt(414)Pgr/Nhs+ (more )
Structure Level Pattern Image Note
TS20: lens vesicle Strong 4C
TS20: olfactory epithelium Strong 4C
TS20: hindbrain Present Regionally restricted 4C Expression is ventral.
TS20: maxillary process Present Regionally restricted 4C Expression is ventral.
TS20: midbrain Present Regionally restricted 4C Expression is ventral.
TS20: spinal cord Present Regionally restricted 4C Expression is ventral.
TS20: mandibular process Present Regionally restricted 4C Expression is dorsal.
TS20: heart Present 4C
TS20: limb epithelium Present Regionally restricted 4C Expression is in the apical ectodermal ridge.
Specimen 4D: embryonic day 12.5; NhsGt(414)Pgr/Nhs+ (more )
Structure Level Pattern Image Note
TS20: lens vesicle Present Regionally restricted 4D Expression is throughout the primary lens fibers.
Specimen 4G: postnatal day 0; NhsGt(414)Pgr/Nhs+ (more )
Structure Level Pattern Image Note
TS27: main olfactory bulb Strong 4G
TS27: medulla oblongata Strong 4G
Specimen 4H: postnatal day 0; NhsGt(414)Pgr/Nhs+ (more )
Structure Level Pattern Image Note
TS27: main olfactory bulb Strong 4H
TS27: medulla oblongata Strong 4H
TS27: hindbrain Present Regionally restricted 4H Expression is ventral.
TS27: midbrain Present Regionally restricted 4H Expression is ventral.
TS27: amygdala Present 4H
TS27: hypothalamus Present 4H
TS27: telencephalon septum Present 4H
Specimen 4I: postnatal adult; NhsGt(414)Pgr/Nhs+ (more )
Structure Level Pattern Image Note
TS28: amygdala Present 4I
TS28: hypothalamus Present 4I
TS28: olfactory tubercle Present 4I
TS28: telencephalon septum Present 4I
Specimen 4J: postnatal adult; NhsGt(414)Pgr/Nhs+ (more )
Structure Level Pattern Image Note
TS28: amygdala Present 4J
TS28: hypothalamus Present 4J
TS28: telencephalon septum Present 4J
TS28: cerebral cortex Weak 4J
TS28: hippocampus Weak 4J
Specimen not shown: embryonic day 9.5; NhsGt(414)Pgr/Nhs+ (more )
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted Expression is in the ventral neural tube.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory