Nhs^Gt(414)Pgr
Gene trapped Allele Detail

Summary

• Symbol: Nhs^Gt(414)Pgr
• Name: NHS actin remodeling regulator; gene trap 414, Peter Gruss
• MGI ID: MGI:4353895
• Gene: Nhs Location: ChrX:160616286-160942437 bp, - strand Genetic Position: ChrX, 74.17 cM
• Alliance: Nhs^Gt(414)Pgr page

Mutation origin

• Mutant Cell Line: 414
• Germline Transmission: Earliest citation of germline transmission: J:151303
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1.8geo Vector Type: gene trap
• The gene trap vector inserted downstream of exon 1. The insertion does not affect normal splicing. (J:151303)

Expression

In Mice Carrying this Mutation:

39 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nhs Mutation: 20 strains or lines available

References

• Original: J:151303 Burdon KP, et al., Mutations in a novel gene, NHS, cause the pleiotropic effects of Nance-Horan syndrome, including severe congenital cataract, dental anomalies, and mental retardation. Am J Hum Genet. 2003 Nov;73(5):1120-30
• All: 1 reference(s)