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Gene Expression Data
Assay Details
Assay
Reference: J:90073 Miyoshi G, et al., Identification of a novel basic helix-loop-helix gene, Heslike, and its role in GABAergic neurogenesis. J Neurosci. 2004 Apr 7;24(14):3672-82
Assay type: RNA in situ
MGI Accession ID: MGI:5780711
Gene symbol: Helt
Gene name: helt bHLH transcription factor
Probe: Heslike probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future midbrain Present Regionally restricted 3A Expression in restricted regions of the rostral mesencephalon.

Specimen 3B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future midbrain Present Regionally restricted 3B Bilateral expression around the alar-basal boundary of the mesencephalon.

Specimen 3C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 3C Expression domain is expanded caudally toward the isthmus (midbrain-hindbrain junction). Rostrally, the expression domain is split into two stripes.
TS17: forebrain-midbrain boundary region Present Regionally restricted 3C Dorsal stripe ends in the pretectum.
TS17: diencephalon Present Regionally restricted 3C Ventral stripe is extended to the zona limitans intrathalamica. Expression in the prethalamus
TS17: telencephalon Present Regionally restricted 3C Expression in the lateral ganglionic eminence.
TS17: olfactory placode Present 3C Expression in the olfactory placode.

Specimen 3D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 3D Expression domain is expanded caudally toward the isthmus.
TS17: forebrain-midbrain boundary region Present Regionally restricted 3D Dorsal stripe ends in the pretectum.
TS17: diencephalon Present Regionally restricted 3D Ventral stripe is extended to the zona limitans intrathalamica. Expression in the prethalamus
TS17: telencephalon Present Regionally restricted 3D Expression in the lateral ganglionic eminence.

Specimen 3E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: midbrain Present Regionally restricted 3E Expression expanded dorsally in the mesencephalon.
TS19: forebrain-midbrain boundary region Present Regionally restricted 3E Expression expanded dorsally in the pretectum.
TS19: diencephalon Present Regionally restricted 3E Expression in zona limitans intrathalamica. Expression in the preoptic area and hypothalamus.
TS19: prethalamus Present 3E Expression in the prethalamus
TS19: telencephalon Present Regionally restricted 3E Expression in the lateral ganglionic eminence.

Specimen 3F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain Present Regionally restricted 3F Expression expanded dorsally in the mesencephalon.
TS20: forebrain-midbrain boundary region Present Regionally restricted 3F Expression expanded dorsally in the pretectum.
TS20: diencephalon Present Regionally restricted 3F Ventral stripe is extended to the zona limitans intrathalamica.
TS20: prethalamus Present 3F Expression in the prethalamus
TS20: hypothalamus Present 3F Expression in the preoptic area and hypothalamus.
TS20: preoptic area Present 3F Expression in the preoptic area and hypothalamus.
TS20: lateral ganglionic eminence Strong 3F

Specimen 3G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: midbrain Present Regionally restricted 3G Expression expanded dorsally in the mesencephalon.
TS21: forebrain-midbrain boundary region Present Regionally restricted 3G Expression expanded dorsally in the pretectum.
TS21: diencephalon Present Regionally restricted 3G The ventral stripe is extended to the zona limitans intrathalamica.
TS21: lateral ganglionic eminence Present 3G

Specimen 3H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: telencephalon subventricular zone Present Regionally restricted 3H Expression in the telencephalon in the subventricular zone.

Specimen 3I: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: rostral migratory stream Present Regionally restricted 3I Expression in the subventricular zone-rostral migratory stream.
TS25: telencephalon subventricular zone Present Regionally restricted 3I Expression in the subventricular zone-rostral migratory stream.

Specimen 3J: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: rostral migratory stream Present 3J Expression in the subventricular zone-rostral migratory stream.

Specimen 3K: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: vomeronasal organ sensory epithelium Present 3K Expression in sensory epithelium of vomeronasal organ.

Specimen 3L: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: vomeronasal organ Present Regionally restricted 3L Expression domain becomes restricted to the basal layer.

Specimen 3M: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: vomeronasal organ Present Regionally restricted 3M Expression in a small region close to the non-sensory epithelium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory