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Cerkltm1.1Npa
Targeted Allele Detail
Summary
Symbol: Cerkltm1.1Npa
Name: ceramide kinase-like; targeted mutation 1.1, Novartis Pharma AG
MGI ID: MGI:5779908
Synonyms: C-CERKLTM2NPA
Gene: Cerkl  Location: Chr2:79162835-79259332 bp, - strand  Genetic Position: Chr2, 47.43 cM
Alliance: Cerkltm1.1Npa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:137892
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  BALB/c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 5. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 5. Cre-mediated recombination removed exon 5. (J:137892)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cerkl Mutation:  29 strains or lines available
References
Original:  J:137892 Graf C, et al., Wild-type levels of ceramide and ceramide-1-phosphate in the retina of ceramide kinase-like-deficient mice. Biochem Biophys Res Commun. 2008 Aug 15;373(1):159-63
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory