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Gene Expression Data
Assay Details
Assay
Reference: J:193306 Yeh HJ, et al., PDGF A-chain gene is expressed by mammalian neurons during development and in maturity. Cell. 1991 Jan 11;64(1):209-16
Assay type: RNA in situ
MGI Accession ID: MGI:5774688
Gene symbol: Pdgfa
Gene name: platelet derived growth factor, alpha
Probe: Pdgfa cDNA7
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1A: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: brainstem Strong 1A
TS26: cerebral cortex Strong 1A
TS26: midbrain Strong 1A
TS26: sympathetic ganglion Strong 1A
TS26: olfactory lobe Strong 1A olfactory bulb
TS26: spinal cord Strong 1A Strongest expression.
Specimen 1B: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: spinal cord Strong Regionally restricted 1B Expressed in the dorsal and ventral gray matter.
TS26: dorsal root ganglion Strong 1B
Specimen 2A/B/C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: amygdala Strong 2A
TS28: corpus striatum Strong 2A
TS28: hypothalamus Strong 2A
TS28: thalamus Strong 2A
TS28: dentate gyrus Strong 2A
TS28: hippocampal formation Strong 2A
TS28: olfactory cortex Strong 2A the cellular layers of the pyriform (olfactory) cortex
TS28: CA1 pyramidal cell layer Strong 2B , 2A
TS28: cerebral cortex Strong 2B , 2A
TS28: CA3 pyramidal cell layer Strong 2C , 2A
Specimen 2D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 2D Expression was much higher than in the adjacent granule cells.
TS28: cerebellum granule cell layer Present 2D
TS28: cerebellum molecular layer Present 2D
Specimen 2F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Strong 2F
Specimen 3A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampal formation Strong Regionally restricted 3A Localized primarily within the large pyramidal cell nuclei, whereas hippocampal interneurons show less intense expression.
Specimen 3B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Strong Regionally restricted 3B The large cortical neurons exhibit a strikingly strong hybridization signal, whereas the smaller glial elements are less uniformly labeled.
Specimen 3C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 3C Expression was much higher than in the adjacent granule cells.
TS28: cerebellum granule cell layer Present 3C
Specimen 3D: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: dorsal root ganglion Strong Regionally restricted 3D Expressed in the neurons within the ganglion, whereas the satellite cells do not show expression.
Specimen not shown: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: embryo Absent
Specimen not shown: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present
Specimen not shown: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: dorsal root ganglion Strong
TS23: spinal cord Strong
TS23: brain Present Expressed at considerably lower levels.
Specimen not shown: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: adrenal gland Weak
TS26: vertebra Weak Regionally restricted Expressed in the hypertrophic chondrocytes.
TS26: long bone Weak Regionally restricted Expressed in the ossification centers.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory