Gene Expression Data
Assay Details
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Assay
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Reference:
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J:119812
Hurd EA, et al., Loss of Chd7 function in gene-trapped reporter mice is embryonic lethal and associated with severe defects in multiple developing tissues. Mamm Genome. 2007 Feb;18(2):94-104
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5767256
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Gene symbol:
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Chd7
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Gene name:
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chromodomain helicase DNA binding protein 7
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
4B:
(close  )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Chd7Gt(S20-7E1)Sor/Chd7+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: hindbrain |
Present |
Non-Uniform |
4B
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Expression was detected throughout with higher levels nearer the ventricular zone and lower levels in differentiated areas of the neuroepithelium.
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| TS22: midbrain |
Present |
Non-Uniform |
4B
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Expression was detected throughout with higher levels nearer the ventricular zone and lower levels in differentiated areas of the neuroepithelium.
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| TS22: telencephalon |
Present |
Non-Uniform |
4B
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Expression was detected throughout with higher levels nearer the ventricular zone and lower levels in differentiated areas of the neuroepithelium.
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| TS22: nasal epithelium |
Present |
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4B
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| TS22: pituitary gland |
Present |
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4B
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Specimen
5A:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Chd7Gt(S20-7E1)Sor/Chd7+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
5B:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Chd7Gt(S20-7E1)Sor/Chd7+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
5C:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Chd7Gt(S20-7E1)Sor/Chd7+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: heart |
Present |
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5C
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Specimen
5D:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Chd7Gt(S20-7E1)Sor/Chd7+
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|
Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
5E:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Chd7Gt(S20-7E1)Sor/Chd7+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: telencephalon |
Present |
Regionally restricted |
5E
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Expression was detected in the olfactory bulb.
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Specimen
5F:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
5G:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
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|
Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
5H:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
5I:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Chd7Gt(S20-7E1)Sor/Chd7+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
5J:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Chd7Gt(S20-7E1)Sor/Chd7+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
5K:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Chd7Gt(S20-7E1)Sor/Chd7+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
5L:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Chd7Gt(S20-7E1)Sor/Chd7+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
6A:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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|
Mutant Allele(s):
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Chd7Gt(S20-7E1)Sor/Chd7+
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|
Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
6B:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
6C:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
|
embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
|
Cryosection
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Specimen
6D:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
|
embryonic day 14.5
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Sex:
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Not Specified
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Type:
|
section
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Embedding:
|
Cryosection
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Specimen
6E:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
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embryonic day 14.5
|
|
Sex:
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Not Specified
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Type:
|
section
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|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: pituitary gland |
Present |
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6E
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Expression was highest in the prospective anterior pituitary and lower in the intermediate and posterior lobes.
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Specimen
6F:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
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Age:
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embryonic day 14.5
|
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Sex:
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Not Specified
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Type:
|
section
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Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: pituitary gland |
Present |
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6F
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Expression was highest in the prospective anterior pituitary and lower in the intermediate and posterior lobes.
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Specimen
6G:
(close )
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Genetic Background:
|
involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
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Not Specified
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Type:
|
section
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Embedding:
|
Cryosection
|
Specimen
6H:
(close )
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Genetic Background:
|
involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
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Type:
|
section
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Embedding:
|
Cryosection
|
Specimen
6I:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
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Type:
|
section
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|
Embedding:
|
Cryosection
|
Specimen
6J:
(close )
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Genetic Background:
|
involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
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Type:
|
section
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Embedding:
|
Cryosection
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Specimen
6K:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
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Type:
|
section
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Embedding:
|
Cryosection
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Specimen
6L:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
|
embryonic day 12.5
|
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Sex:
|
Not Specified
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Type:
|
section
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Embedding:
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Cryosection
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Specimen
not shown E10.5:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
|
section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: future pituitary |
Present |
Non-Uniform |
|
Expression was highest in the prospective anterior pituitary and lower in the intermediate and posterior lobes.
|
Specimen
not shown E12.5:
(close )
|
Genetic Background:
|
involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
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Type:
|
section
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Embedding:
|
Cryosection
|
Specimen
not shown E14.5:
(close )
|
Genetic Background:
|
involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
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Type:
|
section
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|
Embedding:
|
Cryosection
|
Specimen
S1A:
(close )
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Genetic Background:
|
involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
Specimen
S1B:
(close )
|
Genetic Background:
|
involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
Specimen
S1C:
(close )
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Genetic Background:
|
involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
Specimen
S1D:
(close )
|
Genetic Background:
|
involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J
|
|
Mutant Allele(s):
|
Chd7Gt(S20-7E1)Sor/Chd7+
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
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