Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Piezo1tm1.1Apat
Name:	piezo-type mechanosensitive ion channel component 1; targeted mutation 1.1, Ardem Patapoutian
MGI ID:	MGI:5762891
Synonyms:	Piezo1p1-tdT, Piezo1tdT
Gene:	Piezo1  Location: Chr8:123208437-123278068 bp, - strand  Genetic Position: Chr8, 71.31 cM
Alliance:	Piezo1tm1.1Apat page

Germline Transmission:	Earliest citation of germline transmission: J:212179
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Reporter) Mutation:    Insertion   Mutation details: A tdTomato reporter gene and floxed, self-excising neomycin resistance cassette replaced the 3'UTR. The final allele lacks the neomycin resistance cassette. (J:212179)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Piezo1 Mutation:	87 strains or lines available

Original:	J:212179 Ranade SS, et al., Piezo1, a mechanically activated ion channel, is required for vascular development in mice. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10347-52
All:	16 reference(s)