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Gene Expression Data
Assay Details
Assay
Reference: J:137940 Lange UC, et al., Normal germ line establishment in mice carrying a deletion of the Ifitm/Fragilis gene family cluster. Mol Cell Biol. 2008 Aug;28(15):4688-96
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5760372
Gene symbol: Ifitm3
Gene name: interferon induced transmembrane protein 3
Antibody: anti-IFITM3 (FRAGILIS ab15592)
Detection system: Secondary antibody
Results
Specimen 4H EGFP/wt Ifitm3: embryonic day 12.5; Ifitm3tm1Masu/Ifitm3+ (more )
Note: Triple labeled: red - Ifitm3 protein; green - Ifitm3 reporter (assay MGI:5760365); blue - DAPI.
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Present 4H EGFP/wt Ifitm3

Specimen 4H EGFP/EGFP Ifitm3: embryonic day 12.5; Ifitm3tm1Masu/Ifitm3tm1Masu (more )
Note: Triple labeled: red - Ifitm3 protein; green - Ifitm3 reporter (assay MGI:5760365); blue - DAPI.
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Present 4H merge+DAPI (upper right) , 4H EGFP/EGFP Ifitm3

Specimen S4B Del+/- Ifitm3: embryonic day 12.5; Del(7Ifitm5-Ifitm6)1Masu/+ (more )
Note: Triple labeled: red - Ifitm3; green - Oct4 (Pou5f1 assay MGI:5760375); blue - DAPI.
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Present S4B Del+/- merge+DAPI (upper) , S4B Del+/- Ifitm3

Specimen S4B Del-/- Ifitm3: embryonic day 12.5; Del(7Ifitm5-Ifitm6)1Masu/Del(7Ifitm5-Ifitm6)1Masu (more )
Note: Triple labeled: red - Ifitm3; green - Oct4 (Pou5f1 assay MGI:5760375); blue - DAPI.
Structure Level Pattern Image Note
TS20: primordial germ cell of gonad Absent S4B Del-/- Ifitm3 , S4B Del-/- merge+DAPI (lower)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory