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Gene Expression Data
Assay Details
Assay
Reference: J:161846 Westfall JE, et al., Retinal degeneration and failure of photoreceptor outer segment formation in mice with targeted deletion of the Joubert syndrome gene, Ahi1. J Neurosci. 2010 Jun 30;30(26):8759-68
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5751265
Gene symbol: Rab8a
Gene name: RAB8A, member RAS oncogene family
Antibody: anti-Rab8
Detection system: Secondary antibody
Assay notes: Fixative was 1% or 4 % paraformaldehyde.
Results
Specimen 8A Ahi1+/+: embryonic day 18.5 (more )
Note: Double labeled: green - Rab8a; red- - Rho (assay MGI:5751130).
Structure Level Pattern Image Note
TS26: neural retina Present Regionally restricted 8A Ahi1+/+ merge , 8A Ahi1+/+ Rab8a Expression is in photoreceptor neuroblasts.
Specimen 8A Ahi1-/-: embryonic day 18.5; Ahi1tm1Rujf/Ahi1tm1Rujf (more )
Note: Double labeled: green - Rab8a; red- - Rho (assay MGI:5751130).
Structure Level Pattern Image Note
TS26: neural retina Weak Regionally restricted 8A Ahi1-/- merge , 8A Ahi1-/- Rab8a Expression is in photoreceptor neuroblasts.
Specimen 8B Ahi1+/+ top: postnatal (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer Present 8B Ahi1+/+ top
Specimen 8B Ahi1+/+ bottom: postnatal (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer Present 8B Ahi1+/+ bottom
Specimen 8B Ahi1-/- top: postnatal; Ahi1tm1Rujf/Ahi1tm1Rujf (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer Weak 8B Ahi1-/- top
Specimen 8B Ahi1-/- bottom: postnatal; Ahi1tm1Rujf/Ahi1tm1Rujf (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer Weak 8B Ahi1-/- bottom
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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